Evidence map›Paper›PMID 29063080›Full record

ArticleMetallomics : integrated biometal science2017

Studies of copper trafficking in a mouse model of Alzheimer's disease by positron emission tomography: comparison of

Erica M Andreozzi, Julia Baguña Torres, Kavitha Sunassee, Joel Dunn, Simon Walker-Samuel, Istvan Szanda, Philip J Blower

Abstract readComparative Study
In one paragraph

Article in Metallomics : integrated biometal science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Copper homeostasis and cuproptosis in Alzheimer's disease (Review).International journal of molecular medicine · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Teaching the chemical elements in biochemistry: Elemental biology and metallomics.Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology · 2022
    Article
  10. Article
  11. Retinal Vasculopathy in Alzheimer's Disease.Frontiers in neuroscience · 2021
    Review
  12. Article
  13. Imaging of changes in copper trafficking and redistribution in a mouse model of Niemann-Pick C disease using positron emission tomography.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2019
    Article
  14. Review
  15. Insights into Trace Metal Metabolism in Health and Disease from PET: "PET Metallomics".Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2018
    Review
  16. The essential elements of Alzheimer's disease.The Journal of biological chemistry
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Erica M AndreozziDivision of Imaging Sciences, Kings College London, St. Thomas Hospital, London, UK. philip.blower@kcl.ac.uk.
Julia Baguña TorresDivision of Imaging Sciences, Kings College London, St. Thomas Hospital, London, UK. philip.blower@kcl.ac.uk.
Kavitha SunasseeDivision of Imaging Sciences, Kings College London, St. Thomas Hospital, London, UK. philip.blower@kcl.ac.uk.
Joel DunnDivision of Imaging Sciences, Kings College London, St. Thomas Hospital, London, UK. philip.blower@kcl.ac.uk.
Simon Walker-SamuelUCL Centre for Advanced Biomedical Imaging, Division of Medicine, London, UK.ORCID 0000-0003-3530-9166
Istvan SzandaDivision of Imaging Sciences, Kings College London, St. Thomas Hospital, London, UK. philip.blower@kcl.ac.uk.
Philip J BlowerDivision of Imaging Sciences, Kings College London, St. Thomas Hospital, London, UK. philip.blower@kcl.ac.uk.ORCID 0000-0001-6290-1590

Funding

Cancer Research UKDepartment of HealthMedical Research CouncilWellcome Trust 088641Wellcome Trust WT088641/Z/09/Z
6 · The paper itself

Abstract

Alzheimer's disease can involve brain copper dyshomeostasis. We aimed to determine the effect of AD-like pathology on

Indexed as

Disease Models, AnimalAcetatesAdministration, IntravenousAlzheimer DiseaseAnimalsBiological TransportBrainCoordination ComplexesCopper RadioisotopesHumansMetabolic Clearance RateMice, TransgenicOrganometallic CompoundsPositron-Emission TomographyThiosemicarbazonesTissue DistributionAcetatesCoordination ComplexesCopper-64copper (II) diacetyl-di(N(4)-methylthiosemicarbazone)Copper RadioisotopesOrganometallic CompoundsThiosemicarbazones

Identifiers

PMID29063080
PMCPMC6205627

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.