ReviewSynthetic and systems biotechnology2017
Targeted mutagenesis: A sniper-like diversity generator in microbial engineering.
Review in Synthetic and systems biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Hotspots of genetic change in Yersinia pestis.Nature communications · 2025Article
- A Rapid Antibody Enhancement Platform inACS synthetic biology · 2023Article
- Improvements in Bioremediation Agents and Their Modified Strains in Mediating Environmental Pollution.Current microbiology · 2023Review
- Recent advances in screening amino acid overproducers.Engineering microbiology · 2023Review
- High-throughput microbioreactor provides a capable tool for early stage bioprocess development.Scientific reports · 2021Article
- FeedER: a feedback-regulated enzyme-based slow-release system for fed-batch cultivation in microtiter plates.Bioprocess and biosystems engineering · 2019Article
- Tools and systems for evolutionary engineering of biomolecules and microorganisms.Journal of industrial microbiology & biotechnology · 2019Review
- Probing pathways of adaptation with continuous evolution.Current opinion in systems biology · 2019Article
- Tailoring Proteins to Re-Evolve Nature: A Short Review.Molecular biotechnology · 2018Review
- CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window.Nature · 2018Article
- Phage Therapy: What Have We Learned?Viruses · 2018Review
- Directed evolution to improve protein folding in vivo.Current opinion in structural biology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mutations, serving as the raw materials of evolution, have been extensively utilized to increase the chances of engineering molecules or microbes with tailor-made functions. Global and targeted mutagenesis are two main methods of obtaining various mutations, distinguished by the range of action they can cover. While the former one stresses the mining of novel genetic loci within the whole genomic background, targeted mutagenesis performs in a more straightforward manner, bringing evolutionary escape and error catastrophe under control. In this review, we classify the existing techniques of targeted mutagenesis into two categories in terms of whether the diversity is generated
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.