Evidence map›Paper›PMID 29062960›Full record

ArticleSynthetic and systems biotechnology2017

Proteome-wide alterations in an industrial clavulanic acid producing strain of

Eser Ünsaldı, Aslıhan Kurt-Kızıldoğan, Birgit Voigt, Dörte Becher, Gülay Özcengiz

Open access · goldAbstract read
In one paragraph

Article in Synthetic and systems biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Streptomyces clavuligerus: The Omics Era.Journal of industrial microbiology & biotechnology · 2021
    Article
  5. Article
  6. Clavulanic Acid Production byAntibiotics (Basel, Switzerland) · 2021
    Review
  7. Robustifying Experimental Tracer Design forFrontiers in bioengineering and biotechnology · 2021
    Article
  8. Article
  9. Comparative Transcriptome Analysis ofAntibiotics (Basel, Switzerland) · 2019
    Article
  10. Article
  11. Production of β-Lactamase Inhibitors byAntibiotics (Basel, Switzerland) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Eser ÜnsaldıDepartment of Biological Sciences, Middle East Technical University, 06800, Ankara, Turkey.
Aslıhan Kurt-KızıldoğanDepartment of Biological Sciences, Middle East Technical University, 06800, Ankara, Turkey.
Birgit VoigtInstitute of Microbiology, Ernst-Moritz-Arndt-University of Greifswald, D-17487, Greifswald, Germany.
Dörte BecherInstitute of Microbiology, Ernst-Moritz-Arndt-University of Greifswald, D-17487, Greifswald, Germany.
Gülay ÖzcengizDepartment of Biological Sciences, Middle East Technical University, 06800, Ankara, Turkey.
Middle East Technical University · TRUniversität Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The usefulness of genetic/metabolic engineering for further improvement of industrial strains is subject of discussion because of the general lack of knowledge on genetic alterations introduced by iterative cycles of random mutagenesis in such strains. An industrial clavulanic acid (CA)-overproducer

Indexed as

2DEClavulanic acidIndustrial strainMALDI-TOF/MSProteomicsStreptomyces clavuligerus

Identifiers

PMID29062960
PMCPMC5625738
OpenAlexW2547873030

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.