Evidence map›Paper›PMID 29062914›Full record

ArticleWellcome open research2017

The integration site of the

Justin L Tosh, Matthew Rickman, Ellie Rhymes, Frances E Norona, Emma Clayton, Lennart Mucke, Adrian M Isaacs, Elizabeth M C Fisher, Frances K Wiseman

Open access · goldAbstract read
In one paragraph

Article in Wellcome open research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Inhibition of the GSK3β/Nav1.6 complex suppresses early-stage Alzheimer's hyperexcitability.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  4. Transgene Mapping in Animals: What to Choose?International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Synaptic Compensatory Plasticity in Alzheimer's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Humanising the mouse genome piece by piece.Nature communications · 2019
    Review
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Justin L ToshDepartment of Neurodegenerative Disease, Institute of Neurology, University College London, London, WC1N 3BG, UK.ORCID https://orcid.org/0000-0002-1857-995X
Matthew RickmanDepartment of Neurodegenerative Disease, Institute of Neurology, University College London, London, WC1N 3BG, UK.
Ellie RhymesDepartment of Neurodegenerative Disease, Institute of Neurology, University College London, London, WC1N 3BG, UK.
Frances E NoronaDepartment of Neurodegenerative Disease, Institute of Neurology, University College London, London, WC1N 3BG, UK.
Emma ClaytonDepartment of Neurodegenerative Disease, Institute of Neurology, University College London, London, WC1N 3BG, UK.
Lennart MuckeGladstone Institute of Neurological Disease and University of California, San Francisco, CA, 4158, USA.
Adrian M IsaacsDepartment of Neurodegenerative Disease, Institute of Neurology, University College London, London, WC1N 3BG, UK.
Elizabeth M C FisherDepartment of Neurodegenerative Disease, Institute of Neurology, University College London, London, WC1N 3BG, UK.ORCID https://orcid.org/0000-0003-2850-9936
Frances K WisemanDepartment of Neurodegenerative Disease, Institute of Neurology, University College London, London, WC1N 3BG, UK.
University College London · GBGladstone Institutes · USUK Dementia Research Institute · GB

Funding

VIRUS-INDUCED BRAIN PATHOLOGYP50AG005131 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BREWER, JAMES B · 1985 to 2018
$55.4M
UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Steven Dyal Edland · 2019 to 2026
$34.9M
Medical Research Council MR/J004022/1NIA NIH HHS P30 AG062429NIA NIH HHS P50 AG005131Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’s diseaseAmyloid Precursor ProteinAPPJ20mouse modelTransgenicZbtb20

Identifiers

PMID29062914
PMCPMC5645710
OpenAlexW2754387526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.