Evidence map›Paper›PMID 29062910›Full record

ArticleWellcome open research2017

Inhibition of IRE1α-mediated XBP1 mRNA cleavage by XBP1 reveals a novel regulatory process during the unfolded protein response.

Fiona Chalmers, Marcel van Lith, Bernadette Sweeney, Katharine Cain, Neil J Bulleid

Open access · goldAbstract read
In one paragraph

Article in Wellcome open research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Regulation of Age-Related Protein Toxicity.Frontiers in cell and developmental biology · 2021
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Fiona ChalmersInstitute of Molecular, Cellular and Systems Biology, University of Glasgow, Glasgow, G12 8QQ, UK.ORCID https://orcid.org/0000-0002-3026-6753
Marcel van LithInstitute of Molecular, Cellular and Systems Biology, University of Glasgow, Glasgow, G12 8QQ, UK.
Bernadette SweeneyUCB Pharma Slough, Slough, SL1 3WE, UK.
Katharine CainUCB Pharma Slough, Slough, SL1 3WE, UK.
Neil J BulleidInstitute of Molecular, Cellular and Systems Biology, University of Glasgow, Glasgow, G12 8QQ, UK.ORCID https://orcid.org/0000-0002-9839-5279
University of Glasgow · GBUCB Pharma (United Kingdom) · GB

Funding

Biotechnology and Biological Sciences Research Council BB/D00764X/1Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ER stress response.IRE1αUnfolded protein responseXBP1

Identifiers

PMID29062910
PMCPMC5645705
OpenAlexW2623917998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.