Evidence map›Paper›PMID 29062906›Full record

ArticleClinical and experimental hepatology2017

Elevated cystatin C: is it a reflection for kidney or liver impairment in hepatic children?

Behairy El-Sayed, Hanaa El-Araby, Nermin Adawy, Mona Hassona, Naglaa El-Nady, Haidy Zakaria, Mohammed Khedr

Open access · diamondAbstract read
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In one paragraph

Article in Clinical and experimental hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Behairy El-SayedPediatric Hepatology Department, National Liver Institute, Menofyia University, Egypt.
Hanaa El-ArabyPediatric Hepatology Department, National Liver Institute, Menofyia University, Egypt.
Nermin AdawyPediatric Hepatology Department, National Liver Institute, Menofyia University, Egypt.
Mona HassonaClinical Pathology Department, National Liver Institute, Menofyia University, Egypt.
Naglaa El-NadyPediatric Department, Meet-Ghamr Central Hospital, Ministry of Health, Dakahlyia, Egypt.
Haidy ZakariaPediatric Department, Quesna Central Hospital, Ministry of Health, Menofyia, Egypt.
Mohammed KhedrPediatric Hepatology Department, National Liver Institute, Menofyia University, Egypt.
Menoufia University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aim of the studyTo assess if elevated serum cystatin C (Cyst-C) is an indicator for renal or hepatic dysfunction in presence of liver fibrosis. MATERIAL AND

methodsData of 50 children with chronic liver diseases (CLDs), out of which 25 were without renal impairment, and 25 with renal impairment were analyzed. Twenty healthy children served as a healthy control group. Routine investigations, creatinine clearance, hepatitis viral markers, abdominal ultrasonography, and liver biopsy were performed for patients with CLDs. Measurement of serum Cyst-C concentration by particle induced immunonephelometry were completed for both patients and control group.

resultsResults showed that serum Cyst-C is not correlated with the degree of hepatic impairment (

conclusionsSerum Cyst-C is a promising marker to estimate renal impairment in children with CLDs. Further studies are needed to estimate the accuracy of serum Cyst-C for early detection of renal impairment and close monitoring of the hepatic children.

Indexed as

chronic liver diseasecystatin Crenal impairment

Identifiers

PMID29062906
PMCPMC5649481
OpenAlexW2730274894

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.