Evidence map›Paper›PMID 29062842›Full record

ReviewJournal of arthropod-borne diseases2017

Asymptomatic Malaria and its Challenges in the Malaria Elimination Program in Iran: a Systematic Review.

Gholmreza Hassanpour, Mehdi Mohebali, Hojjat Zeraati, Ahmad Raeisi, Hossein Keshavarz

Abstract readReview
In one paragraph

Review in Journal of arthropod-borne diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
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  6. Article
  7. AsymptomaticParasite epidemiology and control · 2023
    Article
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  9. Review
  10. Review
  11. Article
  12. High prevalence of asymptomaticCurrent research in parasitology & vector-borne diseases · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gholmreza HassanpourCenter for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences, Tehran, Iran.
Mehdi MohebaliCenter for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences, Tehran, Iran.
Hojjat ZeraatiDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Ahmad RaeisiCenter for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences, Tehran, Iran.
Hossein KeshavarzCenter for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of this study was to find an appropriate approach to asymptomatic malaria in elimination setting through a systematic review.

methodsA broad search was conducted to find articles with the words 'malaria' in their titles and 'asymptomatic' or 'submicroscopic' in their texts, irrespective of the type of study conducted. The Cochrane, Medline/Pub Med, and Scopus databases, as well as Google Scholar were systematically searched for English articles and reports and Iran's databases-Iran Medex, SID and Magiran were searched for Persian reports and articles, with no time limitation. The study was qualitatively summarized if it contained precise information on the role of asymptomatic malaria in the elimination phase.

resultsSix articles were selected from the initial 2645 articles. The results all re-emphasize the significance of asymptomatic malaria in the elimination phase, and emphasize the significance of diagnostic tests of higher sensitivity to locate these patients and perform interventions to reduce the asymptomatic parasitic reservoirs particularly in regions of low transmission. However, we may infer from the results that the current evidence cannot yet specify an accurate strategy on the role of asymptomatic malaria in the elimination phase.

conclusionTo eliminate malaria, alongside vector control, and treatment of symptomatic and asymptomatic patients, active and inactive methods of case detection need to be employed. The precise monitoring of asymptomatic individuals and submicroscopic cases of malaria through molecular assays and valid serological methods, especially in regions where seasonal and low transmission exists can be very helpful at this phase.

Indexed as

Asymptomatic infectionEliminationMalaria

Identifiers

PMID29062842
PMCPMC5641606

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.