Evidence map›Paper›PMID 29062802›Full record

ArticleAvicenna journal of phytomedicine

Modulation of lung inflammation and immune markers in asthmatic rats treated by

Mahsa Kaveh, Akram Eidi, Ali Nemati, Mohammad Hossein Boskabady

Open access · greenAbstract read
In one paragraph

Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Pharmacologic Mechanisms ofFood science & nutrition · 2025
    Review
  3. An Updated Comprehensive Review of Plants and Herbal Compounds with Antiasthmatic Effect.Evidence-based complementary and alternative medicine : eCAM · 2024
    Review
  4. Review
  5. Phytochemical Characteristics and Anti-Inflammatory, Immunoregulatory, and Antioxidant Effects ofEvidence-based complementary and alternative medicine : eCAM · 2023
    Review
  6. Frontiers in nutrition · 2022
    Article
  7. Effects ofMolecules (Basel, Switzerland) · 2019
    Article
  8. A Pharmacological Review onJournal of pharmacopuncture · 2019
    Review
  9. Hydro-Ethanolic Extract ofIranian journal of pharmaceutical research : IJPR · 2019
    Article
  10. Anti-Inflammatory and Anti-Oxidant Activity ofMolecules (Basel, Switzerland) · 2019
    Article
  11. Polysaccharide extracted fromAmerican journal of translational research · 2018
    Article
  12. An investigation of the effect of purslane (Avicenna journal of phytomedicine
    Article
  13. A comparison between the effects ofAvicenna journal of phytomedicine
    Article
  14. A comparison of the effects ofAvicenna journal of phytomedicine
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mahsa KavehDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Akram EidiDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Ali NematiDepartment of Biochemistry and Biophysics, Faculty of Science, Mashhad Branch, Islamic Azad University, Mashhad, I.R. Iran.
Mohammad Hossein BoskabadyNeurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Islamic Azad University, Science and Research Branch · IRIslamic Azad University, Mashhad · IRMashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePrevious studies indicated anti-inflammatory effects for MATERIALS AND

methodsMale rats were randomly divided into six groups namely, control (group C), sensitized rats (group S), sensitized animal treated with three concentrations of the extract of

resultsThe levels of TP, PLA2 and IgE were significantly increased in the BALF of group S compared to group C (p<0.001 for all cases). However, treatment of S rats with all concentrations of the extract, resulted in a significant and concentration-dependent reduction in BALF levels of TP, PLA2 and IgE compared to group S (p<0.001 for all cases except for the effect of the low extract concentration on TP). Dexamethasone treatment also led to significant reduction of TP, PLA2 and IgE (p<0.001 for all cases). The effect of dexamethasone treatment on PLA2 was significantly higher than the effects of all extract concentrations (p<0.001 for all cases). However, the effect of high extract concentration on TP and IgE was significantly higher than that of dexamethasone (p<0.001 both cases).

conclusionThe results indicated anti-inflammatory and immunomodulatory effects of

Indexed as

AsthmaImmunoglobulin EPhospholibase A2 (PLA2)Portulaca oleraceaSensitized ratTotal protein

Identifiers

PMID29062802
PMCPMC5641415
OpenAlexW2623601508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.