ArticlePlastic and reconstructive surgery. Global open2017
Multimodal Analgesia in Breast Surgical Procedures: Technical and Pharmacological Considerations for Liposomal Bupivacaine Use.
2 registry-linked trialsAbstract read
In one paragraph
Article in Plastic and reconstructive surgery. Global open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pectoral Nerves I, II and Serratus Plane Blocks in Multimodal Analgesia for Mastectomies A Randomized Clinical Trial
Usage Of Artificial Intelligence-Integrated Usg In Application of Pectoral Block In Mastectomies
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Analgesic efficacy of uni-level erector spinae plane block in breast cancer surgery patients: a systematic review and Meta-analysis.BMC anesthesiology · 2026Pooled it
- Liposomal Bupivacaine in Transversus Abdominis Plane Block for Postoperative Pain Control After Autologous Breast Reconstruction: A Systematic Review and Meta-Analysis.Microsurgery · 2025Pooled it
- Multi-agent Preemptive Analgesia Reduces Pain and Shortens Hospital Stay After Mastectomy with Reconstruction.Annals of surgical oncology · 2026Article
- Does Liposomal Bupivacaine Reduce Postoperative Opioid Use in Tissue Expander Based Breast Reconstruction?Aesthetic plastic surgery · 2026Article
- Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block Compared with Conventional Analgesia for Postoperative Analgesia in Breast Cancer Surgery: A Randomized Controlled Trial.Journal of pain research · 2026Article
- Comparison of Pectoral Nerve and Paravertebral Blocks for Postoperative Pain Management in Breast Surgery: A Multicentre Randomised Double-Blind Trial.Journal of breast cancer · 2025Article
- The effect of a local anesthetic cocktail in a serratus anterior plane and PECS 1 block for implant-based breast reconstruction.JPRAS open · 2024Article
- Safety and Distribution of Opioid Prescribing by U.S. Surgeons.Annals of surgery · 2023Article
- Updates on Enhanced Recovery after Surgery protocols for plastic surgery of the breast and future directions.Proceedings (Baylor University. Medical Center) · 2023Article
- Efficacy of PECS block in addition to multimodal analgesia for postoperative pain management in patients undergoing outpatient elective breast surgery: A retrospective study.Frontiers in medicine · 2022Article
- Evaluating the Efficacy of Two Regional Pain Management Modalities in Autologous Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2022Article
- Adoption of Enhanced Recovery after Surgery Protocols in Breast Reconstruction in Alberta Is High before a Formal Program Implementation.Plastic and reconstructive surgery. Global open · 2019Article
- Safe anesthesia for office-based plastic surgery: Proceedings from the PRS Korea 2018 meeting in Seoul, Korea.Archives of plastic surgery · 2019Article
- The Role of Muscle Relaxants – Spasmolytic (Thiocochlicoside) in Postoperative Pain Management after Mastectomy and Breast ReconstructionAsian Pacific journal of cancer prevention : APJCP · 2019Article
- Liposome Bupivacaine Compared to Plain Local Anesthetics to Reduce Postsurgical Pain: An Updated Meta-Analysis of Randomized Controlled Trials.Pain research and treatment · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Anoushka M AfonsoDepartments of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering, New York, N.Y.; Department of Plastic Surgery, Cleveland Clinic Florida, Weston, Fla.; Department of Anesthesiology, Cancer Treatment Centers of America, Newnan, Ga.; Departments of Anesthesiology and Surgery, University of Minnesota, Minneapolis, Minn.; Charlotte Plastic Surgery, Charlotte, N.C.; Department of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Tex.; Department of Plastic Surgery, University of Texas MD Anderson Cancer Center, Houston, Tex; Division of Plastic Surgery, Baylor Scott & White Health, Temple, Tex.; Department of Plastic Surgery, University of Texas Southwestern, Dallas, Tex.; and Department of Anesthesiology, Duke University Medical Center, Durham, N.C.
Martin I NewmanDepartments of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering, New York, N.Y.; Department of Plastic Surgery, Cleveland Clinic Florida, Weston, Fla.; Department of Anesthesiology, Cancer Treatment Centers of America, Newnan, Ga.; Departments of Anesthesiology and Surgery, University of Minnesota, Minneapolis, Minn.; Charlotte Plastic Surgery, Charlotte, N.C.; Department of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Tex.; Department of Plastic Surgery, University of Texas MD Anderson Cancer Center, Houston, Tex; Division of Plastic Surgery, Baylor Scott & White Health, Temple, Tex.; Department of Plastic Surgery, University of Texas Southwestern, Dallas, Tex.; and Department of Anesthesiology, Duke University Medical Center, Durham, N.C.
Neil SeeleyDepartments of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering, New York, N.Y.; Department of Plastic Surgery, Cleveland Clinic Florida, Weston, Fla.; Department of Anesthesiology, Cancer Treatment Centers of America, Newnan, Ga.; Departments of Anesthesiology and Surgery, University of Minnesota, Minneapolis, Minn.; Charlotte Plastic Surgery, Charlotte, N.C.; Department of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Tex.; Department of Plastic Surgery, University of Texas MD Anderson Cancer Center, Houston, Tex; Division of Plastic Surgery, Baylor Scott & White Health, Temple, Tex.; Department of Plastic Surgery, University of Texas Southwestern, Dallas, Tex.; and Department of Anesthesiology, Duke University Medical Center, Durham, N.C.
Jacob HutchinsDepartments of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering, New York, N.Y.; Department of Plastic Surgery, Cleveland Clinic Florida, Weston, Fla.; Department of Anesthesiology, Cancer Treatment Centers of America, Newnan, Ga.; Departments of Anesthesiology and Surgery, University of Minnesota, Minneapolis, Minn.; Charlotte Plastic Surgery, Charlotte, N.C.; Department of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Tex.; Department of Plastic Surgery, University of Texas MD Anderson Cancer Center, Houston, Tex; Division of Plastic Surgery, Baylor Scott & White Health, Temple, Tex.; Department of Plastic Surgery, University of Texas Southwestern, Dallas, Tex.; and Department of Anesthesiology, Duke University Medical Center, Durham, N.C.
Kevin L SmithDepartments of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering, New York, N.Y.; Department of Plastic Surgery, Cleveland Clinic Florida, Weston, Fla.; Department of Anesthesiology, Cancer Treatment Centers of America, Newnan, Ga.; Departments of Anesthesiology and Surgery, University of Minnesota, Minneapolis, Minn.; Charlotte Plastic Surgery, Charlotte, N.C.; Department of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Tex.; Department of Plastic Surgery, University of Texas MD Anderson Cancer Center, Houston, Tex; Division of Plastic Surgery, Baylor Scott & White Health, Temple, Tex.; Department of Plastic Surgery, University of Texas Southwestern, Dallas, Tex.; and Department of Anesthesiology, Duke University Medical Center, Durham, N.C.
Gabriel MenaDepartments of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering, New York, N.Y.; Department of Plastic Surgery, Cleveland Clinic Florida, Weston, Fla.; Department of Anesthesiology, Cancer Treatment Centers of America, Newnan, Ga.; Departments of Anesthesiology and Surgery, University of Minnesota, Minneapolis, Minn.; Charlotte Plastic Surgery, Charlotte, N.C.; Department of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Tex.; Department of Plastic Surgery, University of Texas MD Anderson Cancer Center, Houston, Tex; Division of Plastic Surgery, Baylor Scott & White Health, Temple, Tex.; Department of Plastic Surgery, University of Texas Southwestern, Dallas, Tex.; and Department of Anesthesiology, Duke University Medical Center, Durham, N.C.
Jesse C SelberDepartments of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering, New York, N.Y.; Department of Plastic Surgery, Cleveland Clinic Florida, Weston, Fla.; Department of Anesthesiology, Cancer Treatment Centers of America, Newnan, Ga.; Departments of Anesthesiology and Surgery, University of Minnesota, Minneapolis, Minn.; Charlotte Plastic Surgery, Charlotte, N.C.; Department of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Tex.; Department of Plastic Surgery, University of Texas MD Anderson Cancer Center, Houston, Tex; Division of Plastic Surgery, Baylor Scott & White Health, Temple, Tex.; Department of Plastic Surgery, University of Texas Southwestern, Dallas, Tex.; and Department of Anesthesiology, Duke University Medical Center, Durham, N.C.
Michel H Saint-CyrDepartments of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering, New York, N.Y.; Department of Plastic Surgery, Cleveland Clinic Florida, Weston, Fla.; Department of Anesthesiology, Cancer Treatment Centers of America, Newnan, Ga.; Departments of Anesthesiology and Surgery, University of Minnesota, Minneapolis, Minn.; Charlotte Plastic Surgery, Charlotte, N.C.; Department of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Tex.; Department of Plastic Surgery, University of Texas MD Anderson Cancer Center, Houston, Tex; Division of Plastic Surgery, Baylor Scott & White Health, Temple, Tex.; Department of Plastic Surgery, University of Texas Southwestern, Dallas, Tex.; and Department of Anesthesiology, Duke University Medical Center, Durham, N.C.
Jeffrey C GadsdenDepartments of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering, New York, N.Y.; Department of Plastic Surgery, Cleveland Clinic Florida, Weston, Fla.; Department of Anesthesiology, Cancer Treatment Centers of America, Newnan, Ga.; Departments of Anesthesiology and Surgery, University of Minnesota, Minneapolis, Minn.; Charlotte Plastic Surgery, Charlotte, N.C.; Department of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Tex.; Department of Plastic Surgery, University of Texas MD Anderson Cancer Center, Houston, Tex; Division of Plastic Surgery, Baylor Scott & White Health, Temple, Tex.; Department of Plastic Surgery, University of Texas Southwestern, Dallas, Tex.; and Department of Anesthesiology, Duke University Medical Center, Durham, N.C.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enhanced recovery after surgery is a multidisciplinary perioperative clinical pathway that uses evidence-based interventions to improve the patient experience as well as increase satisfaction, reduce costs, mitigate the surgical stress response, accelerate functional recovery, and decrease perioperative complications. One of the most important elements of enhanced recovery pathways is multimodal pain management. Herein, aspects relating to multimodal analgesia following breast surgical procedures are discussed with the understanding that treatment decisions should be individualized and guided by sound clinical judgment. A review of liposomal bupivacaine, a prolonged-release formulation of bupivacaine, in the management of postoperative pain following breast surgical procedures is presented, and technical guidance regarding optimal administration of liposomal bupivacaine is provided.
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LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
NCT03947463ClinicalTrials.gov
NCT06480045ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.