Evidence map›Paper›PMID 29062441›Full record

ArticleWideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques2017

Is minimally invasive surgical treatment justified for severe acute necrotizing pancreatitis patients with dysfunction of two or more organ systems?

Audrius Šileikis, Emilija Pečiulytė, Agnė Misenkienė, Andrius Klimašauskas, Virgilijus Beiša, Kęstutis Strupas

Abstract read
In one paragraph

Article in Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Audrius ŠileikisClinic of Gastroenterology, Nephrourology and Surgery, Centre of Abdominal Surgery, Vilnius University, Vilnius, Lithuania.
Emilija PečiulytėFaculty of Medicine, Vilnius University, Vilnius, Lithuania.
Agnė MisenkienėFaculty of Medicine, Vilnius University, Vilnius, Lithuania.
Andrius KlimašauskasClinic of Anaesthesiology and Intensive Care, Vilnius University, Vilnius, Lithuania.
Virgilijus BeišaClinic of Gastroenterology, Nephrourology and Surgery, Centre of Abdominal Surgery, Vilnius University, Vilnius, Lithuania.
Kęstutis StrupasClinic of Gastroenterology, Nephrourology and Surgery, Centre of Abdominal Surgery, Vilnius University, Vilnius, Lithuania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWhen minimally invasive therapy was introduced, it became possible to cure some patients without open surgery, or at least delay the operation for longer than a month.

aimTo determine the optimal timing to operate on patients with severe acute necrotizing pancreatitis based on the severity of organ insufficiency. MATERIAL AND

methodsA retrospective analysis was performed in all severe acute necrotizing pancreatitis patients treated in Vilnius University Hospital Santaros Klinikos (VUL SK) from 2007 to 2016. The patients were divided into groups based on the number of dysfunctional organ systems (one or more) and whether the minimally invasive step-up approach to treatment was used.

resultsThe patients with one organ dysfunction had a delay of 35 (without the step-up approach) and 36 (with the step-up approach) days before the open surgery, while the patients with two or more organ systems' dysfunction had almost an identical delay of 28 days, using both surgical treatment methods. The mortality of the patients who had one organ dysfunction and in whom the step-up approach was used was 0%, while in patients without the step-up approach it was 41.7%. In the two or more organ systems' dysfunction group, the mortality for those treated with a step-up approach was 64.3%, and without it 70.7%.

conclusionsThe surgical treatment should be initiated with a minimally invasive procedure. Additionally, the surgery on patients with two or more organ systems' dysfunction should not be delayed for more than one month.

Indexed as

minimally invasive surgeryopen necrosectomysevere necrotizing pancreatitis

Identifiers

PMID29062441
PMCPMC5649498

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.