SynthesisScientific reports2017
Female alcohol consumption and fecundability: a systematic review and dose-response meta-analysis.
Synthesis in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 5 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- The association between caffeine and alcohol consumption and IVF/ICSI outcomes: A systematic review and dose-response meta-analysis.Acta obstetricia et gynecologica Scandinavica · 2022Pooled it
- Family Socioeconomic Position and Lung Cancer Risk: A Meta-Analysis and a Mendelian Randomization Study.Frontiers in public health · 2022Pooled it
- Mendelian randomisation approaches to the study of prenatal exposures: A systematic review.Paediatric and perinatal epidemiology · 2021Pooled it
- Mode of delivery and preterm birth in subsequent births: A systematic review and meta-analysis.PloS one · 2019Pooled it
- Female alcohol consumption and fecundability: a systematic review and dose-response meta-analysis.Scientific reports · 2017Pooled it
- Effectiveness of a nurse-led telephonic brief intervention to reduce risky alcohol use among women in primary care in Brazil: a randomized controlled trial.Archives of women's mental health · 2026Trial
- Increased risk of congenital anomalies after fertility treatment is partially mediated by multiple birth: a population-based cohort study.Human reproduction (Oxford, England) · 2026Article
- Preconception and Early-Pregnancy Alcohol Consumption in Women and Men, Infertility and Risk for Miscarriage.Nutrients · 2026Article
- Infertility and Risk of Congenital Anomalies: A Population-Based Cohort Study.Paediatric and perinatal epidemiology · 2026Article
- Slowing down the clock on ovarian aging-does the ovary hold the secret to the fountain of youth?GeroScience · 2026Review
- Nutrition, Physical Activity and Other Health Aspects Before and During Pregnancy - Recommendations by the Nationwide "Healthy Start Network" (Netzwerk Gesund ins Leben) 2026.Geburtshilfe und Frauenheilkunde · 2026Article
- Ethanol-induced NINJ1 oligomerization might contribute to the lytic death of granulosa cells in PCOS.Human cell · 2026Article
- Associations between life course socioeconomic circumstances and drinking patterns among young and early midlife Finnish public sector employees.Alcohol and alcoholism (Oxford, Oxfordshire) · 2026Article
- Review
- Article
- Position Statement on Cardiometabolic Health Across the Woman's Life Course - 2025.Arquivos brasileiros de cardiologia · 2025Article
- Implantation Failure: Where to Look Up?Journal of clinical medicine · 2025Review
- Health behaviors in women conceiving by medically assisted reproduction vs natural conception: A cross-sectional study of 23,334 nulliparous women.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Lifestyle factors and health outcomes associated with infertility in women: A case-control study using National Health Insurance Database.Reproductive health · 2025Article
- Association between atherogenic index of plasma and infertility: a cross-sectional study based on U.S. women.Lipids in health and disease · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To what extent could alcohol consumption affects female fertility is still unclear. The aim of this study was to quantitatively summarize the dose-response relation between total and specific types of alcohol beverage (beer, wine, and spirits) consumption in female and the fecundability. Four electronic databases were searched. Observational studies (cohort and case-control) that provided female alcohol consumption and fecundity were eligible. Nineteen studies, involving 98657 women, were included in this study. Compared to non-drinkers, the combined estimate (with relative risk, RR) of alcohol consumers on fecundability was 0.87 (95% CI 0.78-0.95) for overall 19 studies. Compared to non-drinkers, the pooled estimates were 0.89 (95% CI 0.82-0.97) for light drinkers (≤12.5 g/day of ethanol) and 0.77 (95% CI 0.61-0.94) for moderate-heavy drinkers (>12.5 g/day of ethanol). Moreover, compared to non-drinkers, the corresponding estimates on fecundability were 0.98 (95% CI 0.85-1.11), 1.02 (95% CI 0.99-1.05), and 0.92 (95% CI 0.83-1.01) for studies focused on wine, beer and spirits, respectively. Dose-response meta-analysis suggested a linear association between decreased fecundability and every 12.5 g/d increasing in alcohol consumption with a RR 0.98 (95% CI 0.97-0.99). This first systematic review and meta-analysis suggested that female alcohol consumption was associated with a reduced fecundability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.