Evidence map›Paper›PMID 29061892›Full record

ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2017

The origin of heredity in protocells.

Timothy West, Victor Sojo, Andrew Pomiankowski, Nick Lane

Open access · hybridAbstract read
In one paragraph

Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 51 citations in OpenAlex.

  1. Biohybrid Computing with Proteinoids and Algae.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. The limits of metabolic heredity in protocells.Proceedings. Biological sciences · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Origin of Life: The Point of No Return.Life (Basel, Switzerland) · 2020
    Article
  10. COProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  11. Possible mechanisms of COInterface focus · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Acetyl Phosphate as a Primordial Energy Currency at the Origin of Life.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2018
    Article
  16. Nascent life cycles and the emergence of higher-level individuality.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017
    Article
  17. Innovation: an emerging focus from cells to societies.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Timothy WestDepartment of Genetics, Evolution and Environment, University College London, Gower Street, London WC1E 6BT, UK.ORCID http://orcid.org/0000-0003-4628-0303
Victor SojoDepartment of Genetics, Evolution and Environment, University College London, Gower Street, London WC1E 6BT, UK.ORCID http://orcid.org/0000-0002-5779-6543
Andrew PomiankowskiDepartment of Genetics, Evolution and Environment, University College London, Gower Street, London WC1E 6BT, UK.ORCID http://orcid.org/0000-0002-5171-8755
Nick LaneDepartment of Genetics, Evolution and Environment, University College London, Gower Street, London WC1E 6BT, UK nick.lane@ucl.ac.uk.ORCID http://orcid.org/0000-0002-5433-3973
University College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we develop a computational model that examines one of the first major biological innovations-the origin of heredity in simple protocells. The model assumes that the earliest protocells were autotrophic, producing organic matter from CO

Indexed as

Biological EvolutionHeredityOrigin of LifeArtificial CellsCell MembraneModels, GeneticThermodynamicscomposomeorigin of lifeprotocellRNA world

Identifiers

PMID29061892
PMCPMC5665807
OpenAlexW2766339080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.