Evidence map›Paper›PMID 29061755›Full record

ArticleAntimicrobial agents and chemotherapy2018

Oral Tobramycin Prophylaxis Prior to Colorectal Surgery Is Not Associated with Systemic Uptake.

T Mulder, M F Q Kluytmans-van den Bergh, R M P H Crolla, A A M Ermens, J Romme, N E Van't Veer, J A J W Kluytmans

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

T MulderJulius Center for Health Sciences and Primary Care, UMC Utrecht, Utrecht, The Netherlands t.mulder-2@umcutrecht.nl.ORCID 0000-0003-4556-0338
M F Q Kluytmans-van den BerghJulius Center for Health Sciences and Primary Care, UMC Utrecht, Utrecht, The Netherlands.
R M P H CrollaDepartment of Surgery, Amphia Hospital, Breda, The Netherlands.
A A M ErmensLaboratory for Clinical Chemistry and Hematology, Amphia Hospital, Breda, The Netherlands.
J RommeLaboratory for Microbiology and Infection Control, Amphia Hospital, Breda, The Netherlands.
N E Van't VeerDepartment of Clinical Pharmacy, Amphia Hospital, Breda, The Netherlands.
J A J W KluytmansJulius Center for Health Sciences and Primary Care, UMC Utrecht, Utrecht, The Netherlands.
Amphia Ziekenhuis · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preoperative oral prophylaxis with nonabsorbable antibiotics has been reported to reduce the risk of surgical site infections after colorectal surgery. This prospective study was conducted to evaluate the risk of toxic side effects by measuring postoperative serum tobramycin levels in patients who received a 3-day prophylaxis with tobramycin and colistin prior to colorectal surgery. In all patients, serum tobramycin concentrations were below the detection limit (0.3 mg/liter), implying a low risk of toxicity.

Indexed as

Administration, OralAgedAnti-Bacterial AgentsAntibiotic ProphylaxisColistinColorectal SurgeryFemaleHumansMaleMiddle AgedProspective StudiesSurgical Wound InfectionTobramycinAnti-Bacterial AgentsColistinTobramycinantibiotic prophylaxissurgerytobramycin

Identifiers

PMID29061755
PMCPMC5740342
OpenAlexW2765873863

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.