Evidence map›Paper›PMID 29061750›Full record

ArticleAntimicrobial agents and chemotherapy2018

Dissemination and Characteristics of a Novel Plasmid-Encoded Carbapenem-Hydrolyzing Class D β-Lactamase, OXA-436, Found in Isolates from Four Patients at Six Different Hospitals in Denmark.

Ørjan Samuelsen, Frank Hansen, Bettina Aasnæs, Henrik Hasman, Bjarte Aarmo Lund, Hanna-Kirsti S Leiros, Berit Lilje, Jessin Janice, Lotte Jakobsen, Pia Littauer and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Beyond the Spotlight:Antibiotics (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Investigation of anInfection prevention in practice · 2022
    Article
  6. Article
  7. Article
  8. Biochemical and biophysical characterization of the OXA-48-like carbapenemase OXA-436.Acta crystallographica. Section F, Structural biology communications · 2021
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. The Global Ascendency of OXA-48-Type Carbapenemases.Clinical microbiology reviews · 2019
    Review
  14. Rapid detection of IMP, NDM, VIM, KPC and OXA-48-like carbapenemases from Enterobacteriales and Gram-negative non-fermenter bacteria by real-time PCR and melt-curve analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

Ørjan SamuelsenNorwegian National Advisory Unit on Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway.
Frank HansenDepartment of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark.
Bettina AasnæsNorwegian National Advisory Unit on Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway.
Henrik HasmanDepartment of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark.
Bjarte Aarmo LundThe Norwegian Structural Biology Centre (NorStruct), Department of Chemistry, UiT, The Arctic University of Norway, Tromsø, Norway.
Hanna-Kirsti S LeirosThe Norwegian Structural Biology Centre (NorStruct), Department of Chemistry, UiT, The Arctic University of Norway, Tromsø, Norway.
Berit LiljeDepartment of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark.
Jessin JaniceNorwegian National Advisory Unit on Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway.
Lotte JakobsenDepartment of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark.
Pia LittauerDepartment of Clinical Microbiology, Hvidovre University Hospital, Hvidovre, Denmark.
Lillian M SøesDepartment of Clinical Microbiology, Slagelse Hospital, Slagelse, Denmark.
Barbara J HolzknechtDepartment of Clinical Microbiology, Slagelse Hospital, Slagelse, Denmark.
Leif P AndersenDepartment of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark.
Marc SteggerDepartment of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark.
Paal S AndersenDepartment of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark.
Anette M HammerumDepartment of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark ama@ssi.dk.
Statens Serum Institut · DKUniversity Hospital of North Norway · NOSlagelse Hospital · DKUiT The Arctic University of Norway · NOHvidovre Hospital · DKRigshospitalet · DK

Funding

Wellcome Trust
6 · The paper itself

Abstract

The diversity of OXA-48-like carbapenemases is continually expanding. In this study, we describe the dissemination and characteristics of a novel carbapenem-hydrolyzing class D β-lactamase (CHDL) named OXA-436. In total, six OXA-436-producing

Indexed as

Bacterial Proteinsbeta-LactamasesCarbapenemsDenmarkEnterobacteriaceaeEnterobacteriaceae InfectionsHumansHydrolysisMicrobial Sensitivity TestsPlasmidsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemscarbapenems

Identifiers

PMID29061750
PMCPMC5740310
OpenAlexW2765592894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.