Evidence map›Paper›PMID 29061736›Full record

ArticleAntimicrobial agents and chemotherapy2018

A Drug Repositioning Approach Reveals that Streptococcus mutans Is Susceptible to a Diverse Range of Established Antimicrobials and Nonantibiotics.

S Saputo, R C Faustoferri, R G Quivey

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Partial in-vitro dispersal ofmicroPublication biology · 2024
    Article
  5. Review
  6. Biofilm · 2023
    Article
  7. Drug Repositioning as a Therapeutic Strategy againstInternational journal of molecular sciences · 2023
    Article
  8. Effect of Extracts, Fractions, and Isolated Molecules ofAntibiotics (Basel, Switzerland) · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Medicinal Chemistry of Inhibitors Targeting Resistant Bacteria.Current topics in medicinal chemistry · 2022
    Article
  13. Small Molecule Compounds, A Novel Strategy againstPathogens (Basel, Switzerland) · 2021
    Review
  14. Article
  15. Review
  16. Article
  17. Frontiers in microbiology · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

S SaputoCenter for Oral Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
R C FaustoferriCenter for Oral Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
R G QuiveyCenter for Oral Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA Robert_Quivey@urmc.rochester.edu.ORCID 0000-0001-8204-838X
University of Rochester · US

Funding

Oxidative Stress Responses in Oral StreptococciR01DE013683 · NIDCR · UNIVERSITY OF ROCHESTER · PI QUIVEY, ROBERT G · 2000 to 2019
$6.2M
Training Program in Oral ScienceT90DE021985 · NIDCR · UNIVERSITY OF ROCHESTER · PI OVITT, CATHERINE, YULE, DAVID I · 2011 to 2021
$5.6M
Fitness profiling of the Streptococcus mutans genomeR01DE017425 · NIDCR · UNIVERSITY OF ROCHESTER · PI QUIVEY, ROBERT G · 2007 to 2011
$3.5M
NIDCR NIH HHS R01 DE013683NIDCR NIH HHS R01 DE017425NIDCR NIH HHS T90 DE021985
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug RepositioningAlcohol DeterrentsAnti-Bacterial AgentsAntifungal AgentsAntineoplastic AgentsBiofilmsDental CariesDental PlaqueDisulfiramHigh-Throughput Screening AssaysHydroxymethylglutaryl-CoA Reductase InhibitorsIon ChannelsMicrobial Sensitivity TestsStreptococcus mutansAlcohol DeterrentsAnti-Bacterial AgentsAntifungal AgentsAntineoplastic AgentsDisulfiramHydroxymethylglutaryl-CoA Reductase InhibitorsIon Channelsantibioticsdental carieshigh-throughput screenStreptococcus mutans

Identifiers

PMID29061736
PMCPMC5740335
OpenAlexW2766833584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.