Evidence map›Paper›PMID 29061720›Full record

ArticleHypertension (Dallas, Tex. : 1979)2017

Role of Kidneys in Sex Differences in Angiotensin II-Induced Hypertension.

Lei Wang, Ximing Wang, Helena Y Qu, Shan Jiang, Jie Zhang, Liying Fu, Jacentha Buggs, Bo Pang, Jin Wei, Ruisheng Liu

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Sex-Specific Differences in Kidney Function and Blood Pressure Regulation.International journal of molecular sciences · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Sex Differences in the Renal Vascular Responses of ATInternational journal of hypertension · 2021
    Article
  13. Gender Differences in Hypertension.Journal of cardiovascular translational research · 2020
    Review
  14. Article
  15. NaHCOHypertension (Dallas, Tex. : 1979) · 2019
    Article
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Lei WangFrom the Department of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa (L.W., X.W., H.Y.Q., S.J., J.Z., B.P., J.W., R.L.); and Pathology (L.F.) and Tampa General Medical Group Transplant Surgery (J.B.), Tampa General Hospital, FL. leiwang@health.usf.edu.
Ximing WangFrom the Department of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa (L.W., X.W., H.Y.Q., S.J., J.Z., B.P., J.W., R.L.); and Pathology (L.F.) and Tampa General Medical Group Transplant Surgery (J.B.), Tampa General Hospital, FL.
Helena Y QuFrom the Department of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa (L.W., X.W., H.Y.Q., S.J., J.Z., B.P., J.W., R.L.); and Pathology (L.F.) and Tampa General Medical Group Transplant Surgery (J.B.), Tampa General Hospital, FL.
Shan JiangFrom the Department of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa (L.W., X.W., H.Y.Q., S.J., J.Z., B.P., J.W., R.L.); and Pathology (L.F.) and Tampa General Medical Group Transplant Surgery (J.B.), Tampa General Hospital, FL.
Jie ZhangFrom the Department of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa (L.W., X.W., H.Y.Q., S.J., J.Z., B.P., J.W., R.L.); and Pathology (L.F.) and Tampa General Medical Group Transplant Surgery (J.B.), Tampa General Hospital, FL.
Liying FuFrom the Department of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa (L.W., X.W., H.Y.Q., S.J., J.Z., B.P., J.W., R.L.); and Pathology (L.F.) and Tampa General Medical Group Transplant Surgery (J.B.), Tampa General Hospital, FL.
Jacentha BuggsFrom the Department of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa (L.W., X.W., H.Y.Q., S.J., J.Z., B.P., J.W., R.L.); and Pathology (L.F.) and Tampa General Medical Group Transplant Surgery (J.B.), Tampa General Hospital, FL.
Bo PangFrom the Department of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa (L.W., X.W., H.Y.Q., S.J., J.Z., B.P., J.W., R.L.); and Pathology (L.F.) and Tampa General Medical Group Transplant Surgery (J.B.), Tampa General Hospital, FL.
Jin WeiFrom the Department of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa (L.W., X.W., H.Y.Q., S.J., J.Z., B.P., J.W., R.L.); and Pathology (L.F.) and Tampa General Medical Group Transplant Surgery (J.B.), Tampa General Hospital, FL.
Ruisheng LiuFrom the Department of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa (L.W., X.W., H.Y.Q., S.J., J.Z., B.P., J.W., R.L.); and Pathology (L.F.) and Tampa General Medical Group Transplant Surgery (J.B.), Tampa General Hospital, FL.
Tampa General Hospital · US

Funding

Tubuloglomerular feedback and salt-sensitive hypertensionR01DK098582 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI LIU, RUISHENG · 2013 to 2016
$1.3M
Primary cilia and modulation of the renal microcirculationR01DK099276 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI LIU, RUISHENG · 2014 to 2017
$980k
NIDDK NIH HHS R01 DK098582NIDDK NIH HHS R01 DK099276
6 · The paper itself

Abstract

The significance of kidneys in regulation of sodium and water balance and hemodynamics has been demonstrated both in patients and animal models. In the present study, we tested our hypothesis that kidneys play an essential role in control of sex differences in angiotensin II (Ang II)-dependent hypertension. Kidney transplantations (KTXs) were performed between male (M) and female (F) C57BL/6 mice (donor→recipient: F→F, M→M, F→M, and M→F). Radiotelemetry transmitters were implanted for measurement of mean arterial pressure during the infusion of Ang II (600 ng·kg

Indexed as

Angiotensin IIAnimalsBlood PressureCytokinesDisease Models, AnimalEndothelin-1FemaleGene Expression RegulationHypertensionKidneyKidney TransplantationMaleMiceMice, Inbred C57BLReceptors, AngiotensinRNAAngiotensin IICytokinesEndothelin-1Receptors, AngiotensinRNASodiumSolute Carrier Family 12, Member 1arterial pressuremice kidney transplantationsex characteristics

Identifiers

PMID29061720
PMCPMC5764100
OpenAlexW2765594417

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.