ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
Presynaptic Neuronal Nicotinic Receptors Differentially Shape Select Inputs to Auditory Thalamus and Are Negatively Impacted by Aging.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 56 citations in OpenAlex.
- Differential cholinergic innervation of lemniscal versus non-lemniscal regions of the inferior colliculus.Journal of chemical neuroanatomy · 2024Article
- Alpha-2 nicotinic acetylcholine receptors regulate spectral integration in auditory cortex.Frontiers in neural circuits · 2024Article
- Increased pyramidal and VIP neuronal excitability in rat primary auditory cortex directly correlates with tinnitus behaviour.The Journal of physiology · 2023Article
- Cholinergic Boutons are Distributed Along the Dendrites and Somata of VIP Neurons in the Inferior Colliculus.Journal of the Association for Research in Otolaryngology : JARO · 2023Article
- Corticothalamic projections deliver enhanced responses to medial geniculate body as a function of the temporal reliability of the stimulus.The Journal of physiology · 2021Article
- Cholinergic boutons are closely associated with excitatory cells and four subtypes of inhibitory cells in the inferior colliculus.Journal of chemical neuroanatomy · 2021Article
- Enzymes of acetylcholine metabolism in the rat inferior colliculus.Brain research · 2021Article
- Mechanisms of GABAergic and cholinergic neurotransmission in auditory thalamus: Impact of aging.Hearing research · 2021Review
- Endogenous Cholinergic Signaling Modulates Sound-Evoked Responses of the Medial Nucleus of the Trapezoid Body.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Supplementary Effect of Choline Alfoscerate on Speech Recognition in Patients With Age-Related Hearing Loss: A Prospective Study in 34 Patients (57 Ears).Frontiers in aging neuroscience · 2021Article
- Multiple Sources of Cholinergic Input to the Superior Olivary Complex.Frontiers in neural circuits · 2021Article
- αFrontiers in neural circuits · 2021Article
- Nicotine evoked efferent transmitter release onto immature cochlear inner hair cells.Journal of neurophysiology · 2020Article
- Regulation of auditory plasticity during critical periods and following hearing loss.Hearing research · 2020Review
- Nicotinic Receptor Subunit Distribution in Auditory Cortex: Impact of Aging on Receptor Number and Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Cholinergic Projections From the Pedunculopontine Tegmental Nucleus Contact Excitatory and Inhibitory Neurons in the Inferior Colliculus.Frontiers in neural circuits · 2020Article
- Top-down or bottom up: decreased stimulus salience increases responses to predictable stimuli of auditory thalamic neurons.The Journal of physiology · 2019Article
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
Abstract
Acetylcholine (ACh) is a potent neuromodulator capable of modifying patterns of acoustic information flow. In auditory cortex, cholinergic systems have been shown to increase salience/gain while suppressing extraneous information. However, the mechanism by which cholinergic circuits shape signal processing in the auditory thalamus (medial geniculate body, MGB) is poorly understood. The present study, in male Fischer Brown Norway rats, seeks to determine the location and function of presynaptic neuronal nicotinic ACh receptors (nAChRs) at the major inputs to MGB and characterize how nAChRs change during aging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.