Evidence map›Paper›PMID 29061669›Full record

ArticleMolecular systems biology2017

Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in

Markus Hartl, Magdalena Füßl, Paul J Boersema, Jan-Oliver Jost, Katharina Kramer, Ahmet Bakirbas, Julia Sindlinger, Magdalena Plöchinger, Dario Leister, Glen Uhrig and 6 more

Open access · goldAbstract read
In one paragraph

Article in Molecular systems biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
24.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it, 148 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Unlocking the molecular secrets ofHorticulture research · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. International journal of molecular sciences · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Structure-function analyses revealCurrent research in structural biology · 2024
    Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 4 countries.

Markus HartlPlant Proteomics, Max Planck Institute for Plant Breeding Research, Cologne, Germany.ORCID 0000-0002-4970-7336
Magdalena FüßlPlant Proteomics, Max Planck Institute for Plant Breeding Research, Cologne, Germany.
Paul J BoersemaProteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany.
Jan-Oliver JostInterfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.
Katharina KramerPlant Proteomics, Max Planck Institute for Plant Breeding Research, Cologne, Germany.
Ahmet BakirbasPlant Proteomics, Max Planck Institute for Plant Breeding Research, Cologne, Germany.
Julia SindlingerInterfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.ORCID 0000-0002-7265-8093
Magdalena PlöchingerPlant Molecular Biology, Department Biology I, Ludwig-Maximilians-University Munich, Martinsried, Germany.
Dario LeisterPlant Molecular Biology, Department Biology I, Ludwig-Maximilians-University Munich, Martinsried, Germany.
Glen UhrigDepartment of Biological Sciences, University of Calgary, Calgary, AB, Canada.
Greg Bg MoorheadDepartment of Biological Sciences, University of Calgary, Calgary, AB, Canada.ORCID 0000-0003-3282-7590
Jürgen CoxProteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany.
Michael E SalvucciUS Department of Agriculture, Agricultural Research Service, Arid-Land Agricultural Research Center, Maricopa, AZ, USA.
Dirk SchwarzerInterfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.ORCID 0000-0002-7477-3319
Matthias MannProteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany.ORCID 0000-0003-1292-4799
Iris FinkemeierPlant Proteomics, Max Planck Institute for Plant Breeding Research, Cologne, Germany iris.finkemeier@uni-muenster.de.ORCID 0000-0002-8972-4026
Max Planck Institute for Plant Breeding Research · DEMax Planck Institute of Biochemistry · DEUniversity of Tübingen · DELudwig-Maximilians-Universität München · DEUniversity of Calgary · CAAgricultural Research Service · USUniversity of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histone deacetylases have central functions in regulating stress defenses and development in plants. However, the knowledge about the deacetylase functions is largely limited to histones, although these enzymes were found in diverse subcellular compartments. In this study, we determined the proteome-wide signatures of the RPD3/HDA1 class of histone deacetylases in

Indexed as

AcetylationArabidopsisArabidopsis ProteinsHistone Deacetylase InhibitorsHistone DeacetylasesHistonesHydroxamic AcidsLysinePeptides, CyclicPlant LeavesProtein Interaction MapsProtein Processing, Post-TranslationalProteomicsapicidinArabidopsis ProteinsHistone Deacetylase InhibitorsHistone DeacetylasesHistonesHydroxamic AcidsLysinePeptides, Cyclictrichostatin AArabidopsishistone deacetylaseslysine acetylationphotosynthesisRuBisCO activase

Identifiers

PMID29061669
PMCPMC5658702
OpenAlexW2766854106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.