Evidence map›Paper›PMID 29061341›Full record

ArticleBiochemical pharmacology2018

Drug resistance induces the upregulation of H

Ashley A Untereiner, Athanasia Pavlidou, Nadiya Druzhyna, Andreas Papapetropoulos, Mark R Hellmich, Csaba Szabo

Open access · greenAbstract read
In one paragraph

Article in Biochemical pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 98 citations in OpenAlex.

  1. Significance of GSH and HRedox report : communications in free radical research · 2026
    Review
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  12. HJournal of nanobiotechnology · 2024
    Article
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  15. HAntioxidants (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ashley A UntereinerDepartment of Anesthesiology, University of Texas Medical Branch, Galveston, TX 77555, USA. Electronic address: ashley.untereiner@utoronto.ca.
Athanasia PavlidouLaboratory of Pharmacology, Faculty of Pharmacy, National and Kapodistrian University of Athens, Greece.
Nadiya DruzhynaDepartment of Anesthesiology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Andreas PapapetropoulosLaboratory of Pharmacology, Faculty of Pharmacy, National and Kapodistrian University of Athens, Greece; Clinical, Experimental Surgery and Translational Research Center, Biomedical Research Foundation of the Academy of Athens, Greece.
Mark R HellmichDepartment of Surgery, University of Texas Medical Branch, Galveston, TX 77555, USA.
Csaba SzaboDepartment of Anesthesiology, University of Texas Medical Branch, Galveston, TX 77555, USA. Electronic address: szabocsaba@aol.com.
The University of Texas Medical Branch at Galveston · USNational and Kapodistrian University of Athens · GR

Funding

Role of Hydrogen Sulfide in Colorectal TumorsR01CA175803 · NCI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI HELLMICH, MARK R, SZABO, CSABA · 2014 to 2018
$1.5M
Therapeutic Repurposing of Benserazide for Colon CancerR21TR001734 · NCATS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SZABO, CSABA · 2016 to 2018
$620k
NCATS NIH HHS R21 TR001734NCI NIH HHS R01 CA175803
6 · The paper itself

Abstract

Hydrogen sulfide (H

Indexed as

Up-RegulationAminooxyacetic AcidAntineoplastic AgentsCell ProliferationCell SurvivalColonic NeoplasmsCystathionine beta-SynthaseDrug Resistance, NeoplasmGene Expression Regulation, EnzymologicGene Expression Regulation, NeoplasticHCT116 CellsHumansHydrogen SulfidePhosphorylationSulfurtransferases3-mercaptopyruvate sulphurtransferaseAminooxyacetic AcidAntineoplastic AgentsCystathionine beta-SynthaseHydrogen SulfideSulfurtransferasesBioenergeticsCancerChemotherapyHydrogen sulfideProliferation

Identifiers

PMID29061341
PMCPMC5866167
OpenAlexW2765928509

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.