ReviewCritical care (London, England)2017
Individualized perfusion targets in hypoxic ischemic brain injury after cardiac arrest.
Review in Critical care (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2025: post-resuscitation care.Intensive care medicine · 2025Guideline
- Determining Optimal Mean Arterial Pressure After Cardiac Arrest: A Systematic Review.Neurocritical care · 2021Pooled it
- Active abdominal compression-decompression cardiopulmonary resuscitation attenuates neuroinflammation associated with TLR4/NF-κB signaling in a rat model of cardiac arrest.Experimental and therapeutic medicine · 2026Article
- Neuroprotection via optimizing cerebral blood flow after cardiac arrest (neuro-intact) study - A phase II proof-of-concept study protocol.Resuscitation plus · 2026Article
- Neuroprognostication After Cardiac Arrest: From Test-Centered Prediction to Ethically Constrained, Longitudinal Decision-Making.Neurocritical care · 2026Article
- Singapore Post-cardiac Arrest Care Guidelines 2026.Singapore medical journal · 2026Review
- The Relationship Between Pressure Reactivity and Cerebral Oximetry Indexes in Patients with Aneurysmal Subarachnoid Hemorrhage: A Single-Center Pilot Study.Neurocritical care · 2025Article
- Association Between Deviations From Cerebral Autoregulation-Derived Optimal Blood Pressure and Outcome After Pediatric Cardiac Arrest.Neurology · 2025Article
- Clinical heterogeneity and phenotyping of post cardiac arrest brain injury: one size may not fit all.Intensive care medicine · 2025Review
- The "SOOTEST-ICU" bundle for optimizing cerebral hypoxia and reperfusion to minimize brain injury after resuscitation from cardiac arrest.World journal of emergency medicine · 2025Article
- Association of cumulative oxygen and carbon dioxide levels with neurologic outcome after pediatric cardiac arrest resuscitation: A multicenter cohort study.Resuscitation plus · 2024Article
- Hypoxic-ischemic brain injury in pig after cardiac arrest - A new histopathological scoring system for non-specialists.Resuscitation plus · 2024Article
- Cerebral Autoregulation: A Target for Improving Neurological Outcomes in Extracorporeal Life Support.Neurocritical care · 2024Review
- Multi-Modal Assessment of Cerebral Hemodynamics in Resuscitated Out-of-Hospital Cardiac Arrest Patients: A Case-Series.Life (Basel, Switzerland) · 2024Article
- Wolf Creek XVII Part 8: Neuroprotection.Resuscitation plus · 2024Review
- Dynamic cerebral autoregulation in postpartum individuals with and without preeclampsia.Pregnancy hypertension · 2023Article
- Hypertonic sodium lactate infusion reduces vasopressor requirements and biomarkers of brain and cardiac injury after experimental cardiac arrest.Critical care (London, England) · 2023Article
- Deviations from PRx-derived optimal blood pressure are associated with mortality after cardiac arrest.Resuscitation · 2022Article
- A comprehensive neuromonitoring approach in a large animal model of cardiac arrest.Animal models and experimental medicine · 2022Article
- Hemodynamic evaluation by serial right heart catheterizations after cardiac arrest; protocol of a sub-study from the Blood Pressure and Oxygenation Targets after Out-of-Hospital Cardiac Arrest-trial (BOX).Resuscitation plus · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Secondary injury is a major determinant of outcome in hypoxic ischemic brain injury (HIBI) after cardiac arrest and may be mitigated by optimizing cerebral oxygen delivery (CDO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.