ArticleBMC geriatrics2017
Antipsychotics and dementia in Canada: a retrospective cross-sectional study of four health sectors.
Article in BMC geriatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Factors Associated with Psychotropic Medication Use in People Living with Dementia in the Community: A Systematic Review and Meta-Analysis.Drugs & aging · 2023Pooled it
- Bipolar Disorder and Manic-Like Symptoms in Alzheimer's, Vascular and Frontotemporal Dementia: A Systematic Review.Current neuropharmacology · 2023Pooled it
- Gender Matters, Age Counts: Patterns of Antipsychotic Prescribing in Canadian Long-Term Care Homes.Healthcare management forum · 2026Article
- Antipsychotic Medication Use Among Newly Admitted Long-term Care Residents During the COVID-19 Pandemic in Canada.Health services insights · 2024Article
- Inter-provincial variation in older home care clients and their pathways: a population-based retrospective cohort study in Canada.BMC geriatrics · 2023Article
- Differences in the longitudinal change of behaviours related to dementia in long-term care: a growth mixture modelling approach.BMC geriatrics · 2023Article
- Long-Term Care Resident Health and Quality of Care During the COVID-19 Pandemic: A Synthesis Analysis of Canadian Institute for Health Information Data Tables.Health services insights · 2023Article
- Cost-effectiveness of a Province-wide Quality Improvement Initiative for Reducing Potentially Inappropriate Use of Antipsychotics in Long-Term Care in British Columbia, Canada.PharmacoEconomics - open · 2021Article
- Pharmacotherapy of Behavioral and Psychological Symptoms of Dementia: State of the Art and Future Progress.Frontiers in pharmacology · 2020Review
- Development of consumer information leaflets for deprescribing in older hospital inpatients: a mixed-methods study.BMJ open · 2019Article
- The interRAI Suite of Mental Health Assessment Instruments: An Integrated System for the Continuum of Care.Frontiers in psychiatry · 2019Review
- Correction to: Antipsychotics and dementia in Canada: a retrospective cross-sectional study of four health sectors.BMC geriatrics · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntipsychotic medications are not recommended for the management of symptoms of dementia, particularly among persons with no behavioral or psychological symptoms. We examine patterns of antipsychotic medication use among persons with dementia across health sectors in Canada, with a focus on factors related to use among those without behavioral or psychotic symptoms.
methodsUsing a retrospective cross-sectional design, this study examines antipsychotic use among adults aged 65 or older with dementia in home care (HC), complex continuing care (CCC), long-term care (LTC), and among alternate level care patients in acute hospitals (ALC). Using clinical data from January 1, 2009 to December 31, 2014, the prevalence of antipsychotic medication use was estimated by the presence of behavioral and psychotic symptoms. Logistic regression was used to identify sector specific factors associated with antipsychotic use in the absence of behavioral and psychotic symptoms.
resultsThe total prevalence of antipsychotic use among older adults with dementia was 19% in HC, 42% in ALC, 35% in CCC, and 37% in LTC. This prevalence ranged from 39% (HC) to 70% (ALC) for those with both behavioral and psychotic symptoms and from 12% (HC) to 32% (ALC) among those with no symptoms. The regression models identified a number of variables were related to antipsychotic use in the absence of behavior or psychotic symptoms, such as bipolar disorder (OR = 5.63 in CCC; OR = 5.52 in LTC), anxious complaints (OR = 1.54 in LTC to 2.01 in CCC), and wandering (OR = 1.83 in ALC).
conclusionsPotentially inappropriate use of antipsychotic medications is prevalent among older adults with dementia across health sectors. The variations in prevalence observed from community to facility based care suggests that system issues may exist in appropriately managing persons with dementia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.