Evidence map›Paper›PMID 29061089›Full record

ArticleThe Journal of neuropsychiatry and clinical neurosciences2018

Dyslexic Characteristics of Chinese-Speaking Semantic Variant of Primary Progressive Aphasia.

Simon Kang Seng Ting, Heidi Foo, Pei Shi Chia, Shahul Hameed, Kok Pin Ng, Adeline Ng, Nagaendran Kandiah

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuropsychiatry and clinical neurosciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Diversity in Alzheimer's disease drug trials: The importance of eligibility criteria.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022
    Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Aphasia in Alzheimer's Disease and Other Dementias (ADOD): Evidence From Chinese.American journal of Alzheimer's disease and other dementias
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Simon Kang Seng TingFrom the Department of Neurology, Singapore General Hospital, Singapore (SKST, PSC, SH); the Department of Neurology, National Neuroscience Institute, Singapore (SKST, HF, PSC, SH, KPN, AN, NK); and Duke-NUS Medical School, Singapore (SKST, SH, NK).
Heidi FooFrom the Department of Neurology, Singapore General Hospital, Singapore (SKST, PSC, SH); the Department of Neurology, National Neuroscience Institute, Singapore (SKST, HF, PSC, SH, KPN, AN, NK); and Duke-NUS Medical School, Singapore (SKST, SH, NK).
Pei Shi ChiaFrom the Department of Neurology, Singapore General Hospital, Singapore (SKST, PSC, SH); the Department of Neurology, National Neuroscience Institute, Singapore (SKST, HF, PSC, SH, KPN, AN, NK); and Duke-NUS Medical School, Singapore (SKST, SH, NK).
Shahul HameedFrom the Department of Neurology, Singapore General Hospital, Singapore (SKST, PSC, SH); the Department of Neurology, National Neuroscience Institute, Singapore (SKST, HF, PSC, SH, KPN, AN, NK); and Duke-NUS Medical School, Singapore (SKST, SH, NK).
Kok Pin NgFrom the Department of Neurology, Singapore General Hospital, Singapore (SKST, PSC, SH); the Department of Neurology, National Neuroscience Institute, Singapore (SKST, HF, PSC, SH, KPN, AN, NK); and Duke-NUS Medical School, Singapore (SKST, SH, NK).
Adeline NgFrom the Department of Neurology, Singapore General Hospital, Singapore (SKST, PSC, SH); the Department of Neurology, National Neuroscience Institute, Singapore (SKST, HF, PSC, SH, KPN, AN, NK); and Duke-NUS Medical School, Singapore (SKST, SH, NK).
Nagaendran KandiahFrom the Department of Neurology, Singapore General Hospital, Singapore (SKST, PSC, SH); the Department of Neurology, National Neuroscience Institute, Singapore (SKST, HF, PSC, SH, KPN, AN, NK); and Duke-NUS Medical School, Singapore (SKST, SH, NK).
National Skin Centre · SG

Funding

NATIONAL ALZHEIMERS COORDINATING CENTER (NACC)U01AG016976 · NIA · UNIVERSITY OF WASHINGTON · PI KUKULL, WALTER ANTHONY · 1999 to 2020
$72.8M
THERAPEUTIC EFFECTS OF INTRA-NASAL INSULIN DETEMIRP50AG005136 · NIA · UNIVERSITY OF WASHINGTON · PI BUCHWALD, DEDRA S · 1985 to 2019
$57.2M
VIRUS-INDUCED BRAIN PATHOLOGYP50AG005131 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GALASKO, DOUGLAS R · 1985 to 2018
$55.4M
WASHINGTON UNIVERSITY ALZHEIMERS DISEASE RESEARCH CENTERP50AG005681 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 1985 to 2019
$52.1M
SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 1991 to 2020
$49.1M
Satellite Diagnostic and Treatment Clinic CoreP50AG008702 · NIA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI DE JAGER, PHILIP L · 1989 to 2019
$46.3M
TREATMENT OF DEPRESSION IN ALZHEIMER'S DISEASEP50AG005133 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BECKER, JAMES T. · 1985 to 2019
$43.0M
THE ROLE OF ADVANCED CAA IN ALZHEIMER'S DEMENTIAP50AG005134 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI GOMEZ-ISLA, TERESA · 1985 to 2018
$42.1M
VASCULAR RISK AND COGNITIVE STATUS IN A LATINO POPULATIONP50AG005142 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BRASKIE, MEREDITH NICOLE · 1985 to 2019
$41.0M
VESICULAR LOCALIZATION AND FUNCTION OF PRESENILIN 1 FRAGMENTP50AG005138 · NIA · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI SEWELL, MARGARET · 1985 to 2019
$37.9M
'T V ASSESSMENT - MEMORY DISORDERED PATIENTS'P50AG005146 · NIA · JOHNS HOPKINS UNIVERSITY · PI TRONCOSO, JUAN · 1985 to 2019
$37.6M
Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI FOROUD, TATIANA M. · 1991 to 2020
$37.3M
NIA NIH HHS P30 AG008017NIA NIH HHS P30 AG008051NIA NIH HHS P30 AG010124NIA NIH HHS P30 AG010129NIA NIH HHS P30 AG010133NIA NIH HHS P30 AG010161NIA NIH HHS P30 AG012300NIA NIH HHS P30 AG013846NIA NIH HHS P30 AG013854NIA NIH HHS P30 AG019610NIA NIH HHS P30 AG028383NIA NIH HHS P30 AG035982NIA NIH HHS P50 AG005131NIA NIH HHS P50 AG005133NIA NIH HHS P50 AG005134NIA NIH HHS P50 AG005136NIA NIH HHS P50 AG005138NIA NIH HHS P50 AG005142NIA NIH HHS P50 AG005146NIA NIH HHS P50 AG005681NIA NIH HHS P50 AG008702NIA NIH HHS P50 AG016570NIA NIH HHS P50 AG016573NIA NIH HHS P50 AG016574NIA NIH HHS P50 AG023501NIA NIH HHS P50 AG025688NIA NIH HHS P50 AG033514NIA NIH HHS P50 AG047266NIA NIH HHS P50 AG047270NIA NIH HHS P50 AG047366NIA NIH HHS U01 AG016976
6 · The paper itself

Abstract

Reading disorder is a recognized feature in primary progressive aphasia (PPA). Surface dyslexia, characterized by regularization errors, is typically seen in the English-speaking semantic variant of PPA (svPPA). However, dyslexic characteristics of other languages, particularly logographical languages such as Chinese, remain sparse in the literature. This study aims to characterize and describe the dyslexic pattern in this group of patients by comparing an English-speaking svPPA group with a Chinese-speaking svPPA group. The authors hypothesized that Chinese-speaking individuals with svPPA would likely commit fewer surface dyslexic errors. By accessing the database of Singapore's National Neuroscience Institute and the National Alzheimer's Coordinating Center of the United States, the authors identified three Chinese-speaking and 18 English-speaking patients with svPPA, respectively, for comparison. The results suggest that, instead of surface dyslexia, svPPA in Chinese-speaking individuals is characterized by a profound deep dyslexic error. Based on current evidence suggesting the role of the temporal pole as a semantic convergence center, the authors conclude that this region also mediates and converges lexical-semantic significance in logographical languages.

Indexed as

SemanticsAgedAphasia, Primary ProgressiveAsian PeopleDatabases, FactualDyslexiaFemaleHumansLanguageMagnetic Resonance ImagingMaleMiddle AgedPositron-Emission TomographyReadingRetrospective StudiesStatistics, NonparametricAphasias and Related DisordersDyslexiaLanguage and Speech DisordersNeuropsychology

Identifiers

PMID29061089
PMCPMC5794526
OpenAlexW2766128383

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.