Evidence map›Paper›PMID 29060062›Full record

ArticleAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference2017

Safe Direct Current Stimulator design for reduced power consumption and increased reliability.

Gene Fridman

Open access · greenAbstract read
In one paragraph

Article in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Vestibular prosthesis: from basic research to clinics.Frontiers in integrative neuroscience · 2023
    Review
  3. On-chip ionic current sensor.Applied physics. A, Materials science & processing · 2021
    Article
  4. Article
  5. A microfluidic system integrated with shape memory alloy valves for a safe direct current delivery system.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2020
    Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Gene Fridman
Johns Hopkins University · US

Funding

Electrical Stimulation to Restore Three Dimensional Vestibular SensationR01DC009255 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI DELLA SANTINA, CHARLES C · 2008 to 2018
$5.7M
Safe Direct Current for Neuroprosthetic ApplicationsR01NS092726 · NINDS · JOHNS HOPKINS UNIVERSITY · PI FRIDMAN, GENE YEVGENY · 2015 to 2019
$1.7M
Safe Direct Current Neural Stimulation SystemR21NS081425 · NINDS · JOHNS HOPKINS UNIVERSITY · PI FRIDMAN, GENE YEVGENY · 2013 to 2014
$443k
Stimulation model and experiments for a vestubular prosthesis.F32DC009917 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI FRIDMAN, GENE YEVGENY · 2008 to 2009
$66k
NIDCD NIH HHS F32 DC009917NIDCD NIH HHS R01 DC009255NINDS NIH HHS R01 NS092726NINDS NIH HHS R21 NS081425
6 · The paper itself

Abstract

Current state of the art neural prosthetics, such as cochlear implants, spinal cord stimulators, and deep brain stimulators use implantable pulse generators (IPGs) to excite neural activity. Inhibition of neural firing is typically indirect and requires excitation of neurons that then have inhibitory projections downstream. Safe Direct Current Stimulator (SDCS) technology is designed to convert electronic pulses delivered to electrodes embedded within an implantable device to ionic direct current (iDC) at the output of the device. iDC from the device can then control neural extracellular potential with the intent of being able to not only excite, but also inhibit and sensitize neurons, thereby greatly expanding the possible applications of neuromodulation therapies and neural interface mechanisms. While the potential applications and proof of concept of this device have been the focus of previous work, the published descriptions of this technology leave significant room for power and reliability optimization. We describe and model a novel device construction designed to reduce power consumption by a factor of 12 and to improve its reliability by a factor of 8.

Indexed as

Electric Stimulation TherapyCochlear ImplantsElectrodes, ImplantedEquipment DesignNervous SystemNeuronsReproducibility of Results

Identifiers

PMID29060062
PMCPMC5911345
OpenAlexW2756385513

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.