Evidence map›Paper›PMID 29059683›Full record

ArticleNature2017

Association analysis identifies 65 new breast cancer risk loci.

Kyriaki Michailidou, Sara Lindström, Joe Dennis, Jonathan Beesley, Shirley Hui, Siddhartha Kar, Audrey Lemaçon, Penny Soucy, Dylan Glubb, Asha Rostamianfar and 352 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Nature, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04331535 (Pragmatic Randomized Trial of Polygenic Risk Scoring for Common Diseases in Primary Care), which is not on this map. Cited by 915 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
915citing papers in PubMed, 9 pooled it
119.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04331535 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Pragmatic Randomized Trial of Polygenic Risk Scoring for Common Diseases in Primary Care

TypeinterventionalSponsorBoston VA Research Institute, Inc.Ran2020 to 2025Enrolled1,076ConditionsCoronary Artery Disease, Atrial Fibrillation, Type 2 Diabetes, Colorectal CancerArmsPolygenic risk score (PRS)
3 · Its place in the literature

Who cites it

915 citing papers in PubMed, 9 syntheses or guidelines pooled it, 1,557 citations in OpenAlex.

  1. Pooled it
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855 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

362 authors at 20 institutions in 31 countries.

Kyriaki MichailidouCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Sara LindströmDepartment of Epidemiology, University of Washington School of Public Health, Seattle, Washington, USA.
Joe DennisCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Jonathan BeesleyDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Shirley HuiThe Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Siddhartha KarCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Audrey LemaçonGenomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Quebec, Canada.
Penny SoucyGenomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Quebec, Canada.
Dylan GlubbDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Asha RostamianfarThe Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Manjeet K BollaCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Qin WangCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Jonathan TyrerCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Ed DicksCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Andrew LeeCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Zhaoming WangDepartment of Computational Biology, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Jamie AllenCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Renske KeemanDivision of Molecular Pathology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Ursula EilberDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Juliet D FrenchDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Xiao Qing ChenDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Laura FachalCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Karen McCueDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Amy E McCart ReedUQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia.
Maya GhoussainiCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Jason S CarrollCancer Research UK Cambridge Research Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, UK.
Xia JiangProgram in Genetic Epidemiology and Statistical Genetics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Hilary FinucaneProgram in Genetic Epidemiology and Statistical Genetics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Marcia AdamsCenter for Inherited Disease Research (CIDR), Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Muriel A AdankDepartment of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands.
Habibul AhsanCenter for Cancer Epidemiology and Prevention, The University of Chicago, Chicago, Illinois, USA.
Kristiina AittomäkiDepartment of Clinical Genetics, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Hoda Anton-CulverDepartment of Epidemiology, University of California Irvine, Irvine, California, USA.
Natalia N AntonenkovaN. N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus.
Volker ArndtDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Kristan J AronsonDepartment of Public Health Sciences, and Cancer Research Institute, Queen's University, Kingston, Ontario, Canada.
Banu ArunDepartment of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Paul L AuerCancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
François BacotMcGill University and Génome Québec Innovation Centre, Montréal, Quebec, Canada.
Myrto BarrdahlDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Caroline BaynesCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Matthias W BeckmannDepartment of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.
Sabine BehrensDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Javier BenitezHuman Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain.
Marina BermishevaInstitute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia.
Leslie BernsteinDepartment of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA.
Carl BlomqvistDepartment of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Natalia V BogdanovaN. N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus.
Stig E BojesenCopenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
Bernardo BonanniDivision of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan, Italy.
Anne-Lise Børresen-DaleDepartment of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway.
Judith S BrandDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Hiltrud BrauchDr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.
Paul BrennanInternational Agency for Research on Cancer, Lyon, France.
Hermann BrennerDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Louise BrintonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Per BrobergDepartment of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden.
Ian W BrockSheffield Institute for Nucleic Acids (SInFoNiA), Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.
Annegien BroeksDivision of Molecular Pathology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Angela Brooks-WilsonGenome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.
Sara Y BruckerDepartment of Gynecology and Obstetrics, University of Tübingen, Tübingen, Germany.
Thomas BrüningInstitute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum, Bochum, Germany.
Barbara BurwinkelDepartment of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.
Katja ButterbachDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Qiuyin CaiDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Hui CaiDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Trinidad CaldésMedical Oncology Department, Hospital Clínico San Carlos, IdISSC (Centro Investigacion Biomedica en Red), CIBERONC (Instituto de Investigación Sanitaria San Carlos), Madrid, Spain.
Federico CanzianGenomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Angel CarracedoGenomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago De Compostela, Spain.
Brian D CarterEpidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA.
Jose E CastelaoOncology and Genetics Unit, Instituto de Investigacion Biomedica (IBI) Orense-Pontevedra-Vigo, Xerencia de Xestion Integrada de Vigo-SERGAS, Vigo, Spain.
Tsun L ChanHong Kong Hereditary Breast Cancer Family Registry, Happy Valley, Hong Kong.
Ting-Yuan David ChengDivision of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, USA.
Kee Seng ChiaSaw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Ji-Yeob ChoiDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea.
Hans ChristiansenDepartment of Radiation Oncology, Hannover Medical School, Hannover, Germany.
Christine L ClarkeWestmead Institute for Medical Research, University of Sydney, Sydney, Australia.
NBCS Collaborators
Margriet ColléeDepartment of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Don M ConroyCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Emilie Cordina-DuvergerCancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France.
Sten CornelissenDivision of Molecular Pathology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
David G CoxDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Angela CoxSheffield Institute for Nucleic Acids (SInFoNiA), Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.
Simon S CrossAcademic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK.
Julie M CunninghamDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Kamila CzeneDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Mary B DalyDepartment of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Peter DevileeDepartment of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Kimberly F DohenyCenter for Inherited Disease Research (CIDR), Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Thilo DörkGynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Isabel Dos-Santos-SilvaDepartment of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Martine DumontGenomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Quebec, Canada.
Lorraine DurcanSouthampton Clinical Trials Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
Miriam DwekDepartment of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, UK.
Diana M EcclesCancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
Arif B EkiciInstitute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.
A Heather EliassenChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Carolina EllbergDepartment of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden.
Mingajeva ElviraDepartment of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russia.
Christoph EngelInstitute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
Mikael ErikssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Peter A FaschingDepartment of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.
Jonine FigueroaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Dieter Flesch-JanysInstitute for Medical Biometrics and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Olivia FletcherBreast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
Henrik FlygerDepartment of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
Lin FritschiSchool of Public Health, Curtin University, Perth, Australia.
Valerie GaborieauInternational Agency for Research on Cancer, Lyon, France.
Marike GabrielsonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Manuela Gago-DominguezGenomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago De Compostela, Spain.
Yu-Tang GaoDepartment of Epidemiology, Shanghai Cancer Institute, Shanghai, China.
Susan M GapsturEpidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA.
José A García-SáenzMedical Oncology Department, Hospital Clínico San Carlos, IdISSC (Centro Investigacion Biomedica en Red), CIBERONC (Instituto de Investigación Sanitaria San Carlos), Madrid, Spain.
Mia M GaudetEpidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA.
Vassilios GeorgouliasDepartment of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece.
Graham G GilesCancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Victoria, Australia.
Gord GlendonFred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.
Mark S GoldbergDepartment of Medicine, McGill University, Montréal, Quebec, Canada.
David E GoldgarDepartment of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Anna González-NeiraHuman Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain.
Grethe I Grenaker AlnæsDepartment of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway.
Mervi GripDepartment of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland.
Jacek GronwaldDepartment of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Anne GrundyCentre de Recherche du Centre Hospitalier de Université de Montréal (CHUM), Université de Montréal, Montréal, Quebec, Canada.
Pascal GuénelCancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France.
Lothar HaeberleDepartment of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.
Eric HahnenCenter for Hereditary Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.
Christopher A HaimanDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Niclas HåkanssonInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Ute HamannMolecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Nathalie HamelMcGill University and Génome Québec Innovation Centre, Montréal, Quebec, Canada.
Susan HankinsonDepartment of Biostatistics & Epidemiology, University of Massachusetts, Amherst, Amherst, Massachusetts, USA.
Patricia HarringtonCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Steven N HartDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Jaana M HartikainenTranslational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.
Mikael HartmanSaw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Alexander HeinDepartment of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.
Jane HeyworthSchool of Population Health, University of Western Australia, Perth, Australia.
Belynda HicksCancer Genomics Research Laboratory (CGR), Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Peter HillemannsGynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Dona N HoDepartment of Pathology, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong.
Antoinette HollestelleDepartment of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Maartje J HooningDepartment of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Robert N HooverDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
John L HopperCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
Ming-Feng HouDivision of Breast Surgery, Department of Surgery, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chia-Ni HsiungInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Guanmengqian HuangMolecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Keith HumphreysDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Junko IshiguroDivision of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan.
Hidemi ItoDivision of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan.
Motoki IwasakiDivision of Epidemiology, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Hiroji IwataDepartment of Breast Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
Anna JakubowskaDepartment of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Wolfgang JanniDepartment of Gynecology and Obstetrics, University Hospital Ulm, Ulm, Germany.
Esther M JohnDepartment of Epidemiology, Cancer Prevention Institute of California, Fremont, California, USA.
Nichola JohnsonBreast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
Kristine JonesCancer Genomics Research Laboratory (CGR), Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Michael JonesDivision of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.
Arja Jukkola-VuorinenDepartment of Oncology, Oulu University Hospital, University of Oulu, Oulu, Finland.
Rudolf KaaksDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Maria KabischMolecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Katarzyna KaczmarekDepartment of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Daehee KangDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea.
Yoshio KasugaDepartment of Surgery, Nagano Matsushiro General Hospital, Nagano, Japan.
Michael J KerinSchool of Medicine, National University of Ireland, Galway, Ireland.
Sofia KhanDepartment of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Elza KhusnutdinovaInstitute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia.
Johanna I KiiskiDepartment of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Sung-Won KimDepartment of Surgery, Daerim Saint Mary's Hospital, Seoul, South Korea.
Julia A KnightProsserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.
Veli-Matti KosmaTranslational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.
Vessela N KristensenDepartment of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway.
Ute KrügerDepartment of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden.
Ava KwongHong Kong Hereditary Breast Cancer Family Registry, Happy Valley, Hong Kong.
Diether LambrechtsVesalius Research Center, VIB, Leuven, Belgium.
Loic Le MarchandUniversity of Hawaii Cancer Center, Honolulu, Hawaii, USA.
Eunjung LeeDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Min Hyuk LeeDepartment of Surgery, Soonchunhyang University College of Medicine and Soonchunhyang University Hospital, Seoul, South Korea.
Jong Won LeeDepartment of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, South Korea.
Chuen Neng LeeDepartment of Surgery, National University Health System, Singapore, Singapore.
Flavio LejbkowiczClalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel.
Jingmei LiDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Jenna LilyquistDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Annika LindblomDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Jolanta LissowskaDepartment of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center & Institute of Oncology, Warsaw, Poland.
Wing-Yee LoDr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.
Sibylle LoiblGerman Breast Group GmbH, Neu Isenburg, Germany.
Jirong LongDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Artitaya LophatananonDivision of Health Sciences, Warwick Medical School, Warwick University, Coventry, UK.
Jan LubinskiDepartment of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Craig LuccariniCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Michael P LuxDepartment of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.
Edmond S K MaHong Kong Hereditary Breast Cancer Family Registry, Happy Valley, Hong Kong.
Robert J MacInnisCancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Victoria, Australia.
Tom MaishmanSouthampton Clinical Trials Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
Enes MakalicCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
Kathleen E MaloneDivision of Public Health Sciences, Epidemiology Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Ivana Maleva KostovskaResearch Centre for Genetic Engineering and Biotechnology "Georgi D. Efremov", Macedonian Academy of Sciences and Arts, Skopje, Republic of Macedonia.
Arto MannermaaTranslational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.
Siranoush ManoukianUnit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan, Italy.
JoAnn E MansonDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Sara MargolinDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Shivaani MariapunCancer Research Malaysia, Subang Jaya, Selangor, Malaysia.
Maria Elena MartinezMoores Cancer Center, University of California San Diego, La Jolla, California, USA.
Keitaro MatsuoDepartment of Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Dimitrios MavroudisDepartment of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece.
James McKayInternational Agency for Research on Cancer, Lyon, France.
Catriona McLeanAnatomical Pathology, The Alfred Hospital, Melbourne, Australia.
Hanne Meijers-HeijboerDepartment of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands.
Alfons MeindlDivision of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany.
Primitiva MenéndezServicio de Anatomía Patológica, Hospital Monte Naranco, Oviedo, Spain.
Usha MenonGynaecological Cancer Research Centre, Department of Women's Cancer, Institute for Women's Health, University College London, London, UK.
Jeffery MeyerDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Hui MiaoSaw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Nicola MillerSchool of Medicine, National University of Ireland, Galway, Ireland.
Nur Aishah Mohd TaibBreast Cancer Research Unit, Cancer Research Institute, University Malaya Medical Centre, Kuala Lumpur, Malaysia.
Kenneth MuirDivision of Health Sciences, Warwick Medical School, Warwick University, Coventry, UK.
Anna Marie MulliganDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Claire MulotUniversité Paris Sorbonne Cité, INSERM UMR-S1147, Paris, France.
Susan L NeuhausenDepartment of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA.
Heli NevanlinnaDepartment of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Patrick NevenLeuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.
Sune F NielsenCopenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
Dong-Young NohDepartment of Surgery, Seoul National University College of Medicine, Seoul, South Korea.
Børge G NordestgaardCopenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
Aaron NormanDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Olufunmilayo I OlopadeCenter for Clinical Cancer Genetics and Global Health, The University of Chicago, Chicago, Illinois, USA.
Janet E OlsonDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Håkan OlssonDepartment of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden.
Curtis OlswoldDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Nick OrrBreast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
V Shane PankratzUniversity of New Mexico Health Sciences Center, University of New Mexico, Albuquerque, New Mexico, USA.
Sue K ParkDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea.
Tjoung-Won Park-SimonGynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Rachel LloydThe Curtin UWA Centre for Genetic Origins of Health and Disease, Curtin University and University of Western Australia, Perth, Australia.
Jose I A PerezServicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain.
Paolo PeterlongoIFOM, The FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy.
Julian PetoDepartment of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Kelly-Anne PhillipsCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
Mila PinchevClalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel.
Dijana Plaseska-KaranfilskaResearch Centre for Genetic Engineering and Biotechnology "Georgi D. Efremov", Macedonian Academy of Sciences and Arts, Skopje, Republic of Macedonia.
Ross PrenticeCancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Nadege PresneauDepartment of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, UK.
Darya ProkofyevaDepartment of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russia.
Elizabeth PughCenter for Inherited Disease Research (CIDR), Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Katri PylkäsLaboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.
Brigitte RackDepartment of Gynecology and Obstetrics, Ludwig-Maximilians University of Munich, Munich, Germany.
Paolo RadiceUnit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan, Italy.
Nazneen RahmanSection of Cancer Genetics, The Institute of Cancer Research, London, UK.
Gadi RennertClalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel.
Hedy S RennertClalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel.
Valerie RheniusCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Atocha RomeroMedical Oncology Department, Hospital Clínico San Carlos, IdISSC (Centro Investigacion Biomedica en Red), CIBERONC (Instituto de Investigación Sanitaria San Carlos), Madrid, Spain.
Jane RommCenter for Inherited Disease Research (CIDR), Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Kathryn J RuddyDepartment of Oncology, Mayo Clinic, Rochester, Minnesota, USA.
Thomas RüdigerInstitute of Pathology, Staedtisches Klinikum Karlsruhe, Karlsruhe, Germany.
Anja RudolphDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Matthias RuebnerDepartment of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.
Emiel J T RutgersDepartment of Surgery, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Emmanouil SaloustrosHereditary Cancer Clinic, University Hospital of Heraklion, Heraklion, Greece.
Dale P SandlerEpidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA.
Suleeporn SangrajrangNational Cancer Institute, Bangkok, Thailand.
Elinor J SawyerResearch Oncology, Guy's Hospital, King's College London, London, UK.
Daniel F SchmidtCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
Rita K SchmutzlerCenter for Hereditary Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.
Andreas SchneeweissDepartment of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.
Minouk J SchoemakerDivision of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.
Fredrick SchumacherDepartment of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA.
Peter SchürmannGynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Rodney J ScottDivision of Molecular Medicine, Pathology North, John Hunter Hospital, Newcastle, Australia.
Christopher ScottDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Sheila SealSection of Cancer Genetics, The Institute of Cancer Research, London, UK.
Caroline SeynaeveDepartment of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Mitul ShahCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Priyanka SharmaDepartment of Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA.
Chen-Yang ShenSchool of Public Health, China Medical University, Taichung, Taiwan.
Grace ShengDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Mark E ShermanDivision of Cancer Prevention, National Cancer Institute, Rockville, Maryland, USA.
Martha J ShrubsoleDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Xiao-Ou ShuDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Ann SmeetsLeuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.
Christof SohnNational Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany.
Melissa C SoutheyGenetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Melbourne, Australia.
John J SpinelliCancer Control Research, BC Cancer Agency, Vancouver, British Columbia, Canada.
Christa StegmaierSaarland Cancer Registry, Saarbrücken, Germany.
Sarah Stewart-BrownDivision of Health Sciences, Warwick Medical School, Warwick University, Coventry, UK.
Jennifer StoneThe Curtin UWA Centre for Genetic Origins of Health and Disease, Curtin University and University of Western Australia, Perth, Australia.
Daniel O StramDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Harald SurowyDepartment of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.
Anthony SwerdlowDivision of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.
Rulla TamimiProgram in Genetic Epidemiology and Statistical Genetics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Jack A TaylorEpidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA.
Maria TengströmTranslational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.
Soo H TeoCancer Research Malaysia, Subang Jaya, Selangor, Malaysia.
Mary Beth TerryDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.
Daniel C TessierMcGill University and Génome Québec Innovation Centre, Montréal, Quebec, Canada.
Somchai ThanasitthichaiNational Cancer Institute, Ministry of Public Health, Nonthaburi, Thailand.
Kathrin ThöneDepartment of Cancer Epidemiology, Clinical Cancer Registry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Rob A E M TollenaarDepartment of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Ian TomlinsonWellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
Ling TongCenter for Cancer Epidemiology and Prevention, The University of Chicago, Chicago, Illinois, USA.
Diana TorresMolecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Thérèse TruongCancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France.
Chiu-Chen TsengDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Shoichiro TsuganeCenter for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Hans-Ulrich UlmerFrauenklinik der Stadtklinik Baden-Baden, Baden-Baden, Germany.
Giske UrsinCancer Registry of Norway, Oslo, Norway.
Michael UntchDepartment of Gynecology and Obstetrics, Helios Clinics Berlin-Buch, Berlin, Germany.
Celine VachonDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Christi J van AsperenDepartment of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.
David Van Den BergDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Ans M W van den OuwelandDepartment of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Lizet van der KolkFamily Cancer Clinic, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Rob B van der LuijtDivision of Biomedical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.
Daniel VincentMcGill University and Génome Québec Innovation Centre, Montréal, Quebec, Canada.
Jason VollenweiderDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Quinten WaisfiszDepartment of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands.
Shan Wang-GohrkeDepartment of Gynaecology and Obstetrics, University of Ulm, Ulm, Germany.
Clarice R WeinbergBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA.
Camilla WendtDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Alice S WhittemoreDepartment of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California, USA.
Hans WildiersLeuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.
Walter WillettDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Robert WinqvistLaboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.
Alicja WolkInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Anna H WuDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Lucy XiaDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Taiki YamajiDivision of Epidemiology, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Xiaohong R YangDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Cheng Har YipSubang Jaya Medical Centre, Subang Jaya, Selangor, Malaysia.
Keun-Young YooSeoul National University College of Medicine, Seoul, South Korea.
Jyh-Cherng YuDepartment of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Wei ZhengDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Ying ZhengShanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Bin ZhuCancer Genomics Research Laboratory (CGR), Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Argyrios ZiogasDepartment of Epidemiology, University of California Irvine, Irvine, California, USA.
Elad ZivDepartment of Medicine, Institute for Human Genetics, UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA.
ABCTB Investigators
ConFab/AOCS Investigators
Sunil R LakhaniUQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia.
Antonis C AntoniouCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Arnaud DroitGenomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Quebec, Canada.
Irene L AndrulisFred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.
Christopher I AmosCenter for Genomic Medicine, Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Fergus J CouchDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Paul D P PharoahCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Jenny Chang-ClaudeDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Per HallDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
David J HunterProgram in Genetic Epidemiology and Statistical Genetics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Roger L MilneCancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Victoria, Australia.
Montserrat García-ClosasDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Marjanka K SchmidtDivision of Molecular Pathology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Stephen J ChanockDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Alison M DunningCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Stacey L EdwardsDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Gary D BaderThe Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Georgia Chenevix-TrenchDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Jacques SimardGenomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Quebec, Canada.
Peter KraftProgram in Genetic Epidemiology and Statistical Genetics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Douglas F EastonCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
University of Cambridge · GBGerman Cancer Research Center · DEKarolinska Institutet · SEUniversity of Southern California · USInstitute of Cancer Research · GBHarvard University · USMayo Clinic · USQIMR Berghofer Medical Research Institute · AUThe University of Melbourne · AUVanderbilt University · USInserm · FRUniversity of Helsinki · FIMedizinische Hochschule Hannover · DEMount Sinai Hospital · CASeoul National University · KRThe Netherlands Cancer Institute · NLAmerican Cancer Society · USCentre hospitalier universitaire de Québec · CAJohns Hopkins University · USOslo University Hospital · NO

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8M
WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Margaret von Mehren · 1985 to 2026
$138.8M
Hormone-Related CancersZIACP010126 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI GIERACH, GRETCHEN · 2009 to 2025
$103.5M
Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
Statistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER · 2000 to 2019
$77.8M
Southern Community Cohort StudyR01CA092447 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLOT, WILLIAM J., ZHENG, WEI · 2001 to 2015
$74.0M
The Role of CHFR in Tumorigenesis and Paclitaxel-Sensitivity in Breast CancerP50CA116201 · NCI · MAYO CLINIC ROCHESTER · PI PETER C LUCAS · 2005 to 2026
$49.9M
CALIFORNIA TEACHERS STUDYR01CA077398 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BERNSTEIN, LESLIE · 1998 to 2014
$29.7M
GENETIC SUSCEPTIBILITY TO CANCER IN MULTIETHNIC COHORTSR01CA063464 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HENDERSON, BRIAN E · 2001 to 2005
$23.2M
Environmental and Genetic Risk Factors For Breast Cancer: The Sister StudyZIAES044005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 2009 to 2025
$22.7M
Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
Oil and Gas as Drivers of Climate Change and Health: Developing unique resources to investigate multi-level and diverse effects of exposure to oil and gas wellsU01CA199277 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI LACEY, JAMES V, MARTINEZ, MARIA ELENA · 2015 to 2024
$20.7M
Cancer Research UK 10118Cancer Research UK 10124Cancer Research UK 15106Cancer Research UK 16561Cancer Research UK 16563Cancer Research UK 19187Cancer Research UK 20411Cancer Research UK 20861Cancer Research UK A16563FIC NIH HHS D43 TW009112Medical Research Council MC_PC_14105NCI NIH HHS K07 CA092044NCI NIH HHS K24 CA169004NCI NIH HHS P01 CA087969NCI NIH HHS P30 CA006927NCI NIH HHS P30 CA023108NCI NIH HHS P30 CA068485NCI NIH HHS P50 CA116201NCI NIH HHS P50 CA125183NCI NIH HHS R01 CA054281NCI NIH HHS R01 CA058860NCI NIH HHS R01 CA063464NCI NIH HHS R01 CA064277NCI NIH HHS R01 CA077398NCI NIH HHS R01 CA089085NCI NIH HHS R01 CA092447NCI NIH HHS R01 CA097396NCI NIH HHS R01 CA100374NCI NIH HHS R01 CA120120NCI NIH HHS R01 CA121941NCI NIH HHS R01 CA128978NCI NIH HHS R01 CA132839NCI NIH HHS R01 CA140286NCI NIH HHS R01 CA148667NCI NIH HHS R01 CA159868NCI NIH HHS R01 CA176785NCI NIH HHS R01 CA184585NCI NIH HHS R01 CA192393NCI NIH HHS R25 CA092049NCI NIH HHS R35 CA197449NCI NIH HHS R37 CA070867NCI NIH HHS U01 CA098758NCI NIH HHS U01 CA116167NCI NIH HHS U01 CA122171NCI NIH HHS U01 CA194393NCI NIH HHS U01 CA199277NCI NIH HHS U19 CA148065NCI NIH HHS UM1 CA164917NCI NIH HHS UM1 CA164920NCI NIH HHS UM1 CA164973NCI NIH HHS UM1 CA176726NCI NIH HHS UM1 CA182910NCI NIH HHS UM1 CA186107NHGRI NIH HHS R01 HG009979NHGRI NIH HHS U41 HG006623NIGMS NIH HHS P41 GM103504NIMH NIH HHS R01 MH101244World Health Organization 001
6 · The paper itself

Abstract

Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. However, much of the genetic contribution to breast cancer risk remains unknown. Here we report the results of a genome-wide association study of breast cancer in 122,977 cases and 105,974 controls of European ancestry and 14,068 cases and 13,104 controls of East Asian ancestry. We identified 65 new loci that are associated with overall breast cancer risk at P < 5 × 10

Indexed as

Genetic LociGenome-Wide Association StudyAsiaAsian PeopleBinding SitesBreast NeoplasmsComputer SimulationEuropeFemaleGenetic Predisposition to DiseaseHumansMultifactorial InheritancePolymorphism, Single NucleotideRegulatory Sequences, Nucleic AcidRisk AssessmentTranscription FactorsTranscription Factors

Identifiers

PMID29059683
PMCPMC5798588
OpenAlexW2765253743

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