Evidence map›Paper›PMID 29059032›Full record

ArticleInternational journal of STD & AIDS2018

Rapid testing and treatment for sexually transmitted infections improve patient care and yield public health benefits.

Gary G Whitlock, Daniel C Gibbons, Nick Longford, Michael J Harvey, Alan McOwan, Elisabeth J Adams

Abstract read
In one paragraph

Article in International journal of STD & AIDS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Observational
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  17. Potential for Point-of-Care Tests to Reduce Chlamydia-associated Burden in the United States: A Mathematical Modeling Analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
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  20. Evaluation of the performance of the Cepheid Xpert HIV-1 Viral Load Assay for quantitative and diagnostic uses.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gary G Whitlock1 GUM/HIV, Chelsea and Westminster NHS Foundation Trust, London, UK.
Daniel C Gibbons2 Aquarius Population Health Limited, London, UK.
Nick Longford4 Division of Medicine, Imperial College London, London, UK.
Michael J Harvey2 Aquarius Population Health Limited, London, UK.
Alan McOwan1 GUM/HIV, Chelsea and Westminster NHS Foundation Trust, London, UK.
Elisabeth J Adams2 Aquarius Population Health Limited, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A service evaluation of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) testing and result notification in patients attending a rapid testing service (Dean Street Express [DSE]) compared with those attending an existing 'standard' sexual health clinic (56 Dean Street [56DS]), and modelling the impact of the new service from 1 June 2014 to 31 May 2015. PRIMARY OUTCOME: time from patients' sample collection to notification of test results at DSE compared with 56DS. Secondary outcomes estimated using a model: number of transmissions prevented and the number of new partner visits avoided and associated cost savings achieved due to rapid testing at DSE. In 2014/15, there were a total of 81,352 visits for CT/NG testing across 56DS (21,086) and DSE (60,266). Rapid testing resulted in a reduced mean time to notification of 8.68 days: 8.95 days for 56DS (95% CI 8.91-8.99) compared to 0.27 days for DSE (95% CI 0.26-0.28). Our model estimates that rapid testing at DSE would lead to 196 CT and/or NG transmissions prevented (2.5-97.5% centile range = 6-956) and lead to annual savings attributable to reduced numbers of partner attendances of £124,283 (2.5-97.5% centile range = £4260-590,331). DSE, a rapid testing service for asymptomatic infections, delivers faster time to result notification for CT and/or NG which enables faster treatment, reduces infectious periods and leads to fewer transmissions, partner attendances and clinic costs.

Indexed as

Sexual BehaviorAdultChlamydia InfectionsChlamydia trachomatisFemaleGonorrheaHumansMaleNeisseria gonorrhoeaePatient CarePoint-of-Care TestingPublic HealthSexually Transmitted DiseasesSexual PartnersUnited KingdomChlamydia (Chlamydia trachomatis)gonorrhoea (Neisseria gonorrhoeae)sexual behaviour

Identifiers

PMID29059032
PMCPMC5844454

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.