Evidence map›Paper›PMID 29058621›Full record

SynthesisMalaria journal2017

A systematic review and synthesis of the strengths and limitations of measuring malaria mortality through verbal autopsy.

Samantha Herrera, Yeetey Enuameh, George Adjei, Kenneth Ayuurebobi Ae-Ngibise, Kwaku Poku Asante, Osman Sankoh, Seth Owusu-Agyei, Yazoume Yé

Abstract readSystematic Review
In one paragraph

Synthesis in Malaria journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Article
  6. A Qualitative Method To Assess a History of Cerebral Malaria in Malian Children.The American journal of tropical medicine and hygiene · 2025
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  11. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Samantha HerreraMEASURE Evaluation, ICF, 530 Gaither Road, Suite 500, Rockville, MD, 20850, USA. Samantha.Herrera@icf.com.ORCID 0000-0001-7597-5249
Yeetey EnuamehKintampo Health Research Centre, Kintampo, Ghana.
George AdjeiKintampo Health Research Centre, Kintampo, Ghana.
Kenneth Ayuurebobi Ae-NgibiseKintampo Health Research Centre, Kintampo, Ghana.
Kwaku Poku AsanteKintampo Health Research Centre, Kintampo, Ghana.
Osman SankohINDEPTH Network, 38 & 40 Mensah Wood Street, East Legon, Accra, Ghana.
Seth Owusu-AgyeiKintampo Health Research Centre, Kintampo, Ghana.
Yazoume YéMEASURE Evaluation, ICF, 530 Gaither Road, Suite 500, Rockville, MD, 20850, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLack of valid and reliable data on malaria deaths continues to be a problem that plagues the global health community. To address this gap, the verbal autopsy (VA) method was developed to ascertain cause of death at the population level. Despite the adoption and wide use of VA, there are many recognized limitations of VA tools and methods, especially for measuring malaria mortality. This study synthesizes the strengths and limitations of existing VA tools and methods for measuring malaria mortality (MM) in low- and middle-income countries through a systematic literature review.

methodsThe authors searched PubMed, Cochrane Library, Popline, WHOLIS, Google Scholar, and INDEPTH Network Health and Demographic Surveillance System sites' websites from 1 January 1990 to 15 January 2016 for articles and reports on MM measurement through VA. INCLUSION CRITERIA: article presented results from a VA study where malaria was a cause of death; article discussed limitations/challenges related to measurement of MM through VA. Two authors independently searched the databases and websites and conducted a synthesis of articles using a standard matrix.

resultsThe authors identified 828 publications; 88 were included in the final review. Most publications were VA studies; others were systematic reviews discussing VA tools or methods; editorials or commentaries; and studies using VA data to develop MM estimates. The main limitation were low sensitivity and specificity of VA tools for measuring MM. Other limitations included lack of standardized VA tools and methods, lack of a 'true' gold standard to assess accuracy of VA malaria mortality.

conclusionsExisting VA tools and methods for measuring MM have limitations. Given the need for data to measure progress toward the World Health Organization's Global Technical Strategy for Malaria 2016-2030 goals, the malaria community should define strategies for improving MM estimates, including exploring whether VA tools and methods could be further improved. Longer term strategies should focus on improving countries' vital registration systems for more robust and timely cause of death data.

Indexed as

AutopsyHumansInterviews as TopicMalariaSensitivity and SpecificityCause-specific mortalityMalaria mortalityVerbal autopsy

Identifiers

PMID29058621
PMCPMC5651608

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.