Evidence map›Paper›PMID 29058461›Full record

ArticleAIDS care2018

Caregiver role in HIV medication adherence among HIV-infected orphans in Tanzania.

Margaret W Gichane, Kristen A Sullivan, Aisa M Shayo, Blandina T Mmbaga, Karen O' Donnell, Coleen K Cunningham, Dorothy E Dow

Registry-linked trialAbstract read
In one paragraph

Article in AIDS care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02888288 (Integrating Mental Health Into a HIV Clinic to Improve Outcomes Among Tanzanian Youth), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02888288 nacompletednot on this map

Integrating Mental Health Into a HIV Clinic to Improve Outcomes Among Tanzanian Youth

TypeinterventionalSponsorDuke UniversityRan2016 to 2020Enrolled140ConditionsHealth Behavior, HIV, Mental HealthArmsMental Health Intervention, Standard of Care
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Margaret W Gichanea Center for Health Policy & Inequalities Research, Duke Global Health Institute , Duke University , Durham , USA.
Kristen A Sullivana Center for Health Policy & Inequalities Research, Duke Global Health Institute , Duke University , Durham , USA.
Aisa M Shayoe Pediatric and Child Health Department , Kilimanjaro Christian Medical Centre , Moshi , Tanzania.
Blandina T Mmbagad Kilimanjaro Christian Medical Centre-Duke Collaboration , Moshi , Tanzania.
Karen O' Donnella Center for Health Policy & Inequalities Research, Duke Global Health Institute , Duke University , Durham , USA.
Coleen K Cunninghamg Department of Pediatrics, Division of Pediatric Infectious Diseases , Duke University Medical Center , Durham , USA.
Dorothy E Dowd Kilimanjaro Christian Medical Centre-Duke Collaboration , Moshi , Tanzania.
Duke University · USKilimanjaro Christian Medical Centre · TZDuke Institute for Health Innovation · USDuke Medical Center · USUniversity of North Carolina at Chapel Hill · US

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
Vanderbilt-Emory-Cornell-Duke Global Health Fellowship Consortium-Expanding Diversity for Global Equity (EDGE)D43TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALIYU, MUKTAR HASSAN, HEIMBURGER, DOUGLAS CORBETT · 2017 to 2021
$6.3M
Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
Institutional Training Grant in Pediatric Infectious DiseaseT32HD060558 · NICHD · DUKE UNIVERSITY · PI CUNNINGHAM, COLEEN K. · 2011 to 2015
$1.0M
Integrating Mental Health into a HIV Clinic to Improve Outcomes in Tanzanian YouthK01TW009985 · FIC · DUKE UNIVERSITY · PI DOW, DOROTHY E. · 2015 to 2019
$667k
FIC NIH HHS D43 TW009337FIC NIH HHS K01 TW009985FIC NIH HHS R25 TW009337NIAID NIH HHS P30 AI064518NICHD NIH HHS T32 HD060558
6 · The paper itself

Abstract

Youth living with HIV in sub-Saharan Africa face numerous challenges in adhering to HIV treatment. The AIDS epidemic has left many of these youth orphaned due to AIDS-related death of one or both parents. It is imperative to understand the family context of youth living with HIV in order to develop responsive interventions to improve adherence to antiretroviral therapy. We conducted qualitative in-depth interviews with 17 HIV-infected AIDS orphans, ages 13-24 years, screened positive for mental health difficulties according to the Patient Health Questionaire-9 (PHQ-9) or UCLA PTSD Reaction Index (PTSD-RI), and receiving outpatient HIV care at an adolescent medical clinic in Moshi, Tanzania. Treatment-related support varied by orphan status. Paternal orphans cared for by their biological mothers and maternal orphans cared for by grandmothers described adherence support such as assistance taking medication and attending clinic. Double orphans did not report adherence support. Several maternal and double orphans faced direct interference from caregivers and household members when they attempted to take their medications. Caregivers play a significant role in treatment adherence and must be considered in interventions to increase medication adherence in HIV-infected orphans. Findings from this study informed caregiver participation in Sauti ya Vijana (The Voice of Youth), a mental health intervention for youth living with HIV in Tanzania.

Indexed as

CaregiversChild, OrphanedMedication AdherenceAdolescentAnti-HIV AgentsFemaleHIV InfectionsHumansMaleTanzaniaYoung AdultAnti-HIV AgentsadolescentAIDS orphancaregiverHIV-infectedmedication adherence

Identifiers

PMID29058461
PMCPMC5895501
OpenAlexW2765723299

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.