Evidence map›Paper›PMID 29058252›Full record

ArticleWorld journal of pediatrics : WJP2017

A transversal pilot study of oropharyngeal carriage of Kingella kingae in healthy children younger than 6 months.

Vasiliki Spyropoulou, Gabriel Brändle, Albane Bertha Rosa Maggio, Rebecca Anderson Della Llana, Abdessalam Cherkaoui, Gesuele Renzi, Jacques Schrenzel, Sergio Manzano, Dimitri Ceroni

Abstract read
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In one paragraph

Article in World journal of pediatrics : WJP, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vasiliki SpyropoulouChild and Adolescent Department, University Hospitals of Geneva, Str Willy-Donzé 6, CH-1211, Geneva 14, Switzerland. vasiliki.spyropoulou@hcuge.ch.
Gabriel BrändleChild and Adolescent Department, University Hospitals of Geneva, Str Willy-Donzé 6, CH-1211, Geneva 14, Switzerland.
Albane Bertha Rosa MaggioPediatric Sport Medicine and Obesity Care Program, University Hospitals of Geneva, Geneva, Switzerland.
Rebecca Anderson Della LlanaIntensive Care Unit, University Hospitals of Geneva, Geneva, Switzerland.
Abdessalam CherkaouiClinical Microbiology Laboratory, Service of Infectious Diseases, University Hospitals of Geneva, Geneva, Switzerland.
Gesuele RenziClinical Microbiology Laboratory, Service of Infectious Diseases, University Hospitals of Geneva, Geneva, Switzerland.
Jacques SchrenzelClinical Microbiology Laboratory, Service of Infectious Diseases, University Hospitals of Geneva, Geneva, Switzerland.
Sergio ManzanoPediatric Emergency Division, University Hospitals of Geneva, Geneva, Switzerland.
Dimitri CeroniPediatric Orthopedic Service, University Hospitals of Geneva, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this pilot study was to investigate the extent of oropharyngeal Kingella kingae carriage during the first 6 months of life.

methodsWe conducted a monocentric transversal pilot study on healthy children younger than 6 months in order to define the oropharyngeal carriage rate. Participants were recruited between December 2013 and September 2015 among children without symptoms or signs of invasive infections.

resultsWe demonstrated an oropharyngeal carriage rate of 0.67% in children younger than 6 months. Due to the really low carriage rate, it was not possible to draw statistically significant conclusion about any other characteristic of our population.

conclusionsThe present study suggests that the oropharyngeal carriage of Kingella kingae among a Swiss population of healthy infants younger than 6 months is exceptional. The scarcity of colonization and disease in the early months of life suggests thus that defense against mucosal carriage and invasive infection is above all provided by vertically acquired immunity. Limited exposure of the neonates due to limited social contacts may also represent another factor avoiding neonates' mucosal Kingella kingae carriage.

Indexed as

Age FactorsCarrier StateCohort StudiesFemaleHealthy VolunteersHumansIncidenceInfantInfant, NewbornKingella kingaeMaleNeisseriaceae InfectionsOropharynxPilot ProjectsProspective StudiesRisk AssessmentKingella kingaeoropharyngeal carriageyoung infants

Identifiers

PMID29058252

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.