Evidence map›Paper›PMID 29058185›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2018

Simultaneous Real-Time Measurement of the β-Cell Membrane Potential and Ca

Nicholas C Vierra, Matthew T Dickerson, Louis H Philipson, David A Jacobson

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. The Pancreatic β-Cell: The Perfect Redox System.Antioxidants (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nicholas C VierraDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.
Matthew T DickersonDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.
Louis H PhilipsonDepartment of Medicine, Kovler Diabetes Center, The University of Chicago, Chicago, IL, USA.
David A JacobsonDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA. david.a.jacobson@vanderbilt.edu.
Vanderbilt University · USUniversity of Chicago · US

Funding

Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OWEN P MCGUINNESS · 2012 to 2026
$29.3M
Pilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI Matthew J Brady · 2013 to 2026
$20.9M
MULTIDISCIPLINARY TRAINING IN MOLECULAR ENDOCRINOLOGYT32DK007563 · NIDDK · VANDERBILT UNIVERSITY · PI Richard M O'Brien · 1988 to 2026
$15.9M
Integrated Training in Engineering and DiabetesT32DK101003 · NIDDK · VANDERBILT UNIVERSITY · PI Jamey D. Young · 2014 to 2026
$3.9M
Two-Pore-Domain Potassium Channels as Novel Targets for Modulating Islet Hormone SecretionR01DK097392 · NIDDK · VANDERBILT UNIVERSITY · PI JACOBSON, DAVID AARON · 2013 to 2022
$3.3M
POTASSIUM CHANNEL EXPRESSION IN PANCREATIC B CELLSR01DK048494 · NIDDK · UNIVERSITY OF CHICAGO · PI PHILIPSON, LOUIS H. · 1995 to 2011
$2.8M
Molecular Physiology of Store-Dependant Calcium Entry in Pancreatic Beta Cells.R01DK092616 · NIDDK · UPSTATE MEDICAL UNIVERSITY · PI ROE, MICHAEL WILLIAM · 2012 to 2015
$1.9M
Designing selective TALK-1 inhibitors to reduce beta-cell dysfunction in diabetesR01DK115620 · NIDDK · VANDERBILT UNIVERSITY · PI JACOBSON, DAVID AARON · 2018 to 2021
$1.6M
Secretagogue Induced Mechanisms Regulating Islet Electrical ActivityK01DK081666 · NIDDK · VANDERBILT UNIVERSITY · PI JACOBSON, DAVID AARON · 2009 to 2012
$505k
TALK-1 channels as a novel target to modulate basal insulin secretion and obesityF31DK109625 · NIDDK · VANDERBILT UNIVERSITY · PI VIERRA, NICHOLAS CATIN · 2016 to 2017
$42k
NIDDK NIH HHS F31 DK109625NIDDK NIH HHS K01 DK081666NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK020595NIDDK NIH HHS R01 DK048494NIDDK NIH HHS R01 DK092616NIDDK NIH HHS R01 DK097392NIDDK NIH HHS R01 DK115620NIDDK NIH HHS T32 DK007563NIDDK NIH HHS T32 DK101003
6 · The paper itself

Abstract

Stimulus-secretion coupling in pancreatic β-cells requires Ca

Indexed as

AnimalsCalciumCells, CulturedHumansInsulin-Secreting CellsMembrane PotentialsMicePatch-Clamp TechniquesPotassium ChannelsCalciumPotassium ChannelsCalcium imagingFluo-4 AMMembrane potentialPancreatic β-cellPotassium channels

Identifiers

PMID29058185
PMCPMC5927608
OpenAlexW2766836708

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.