ArticleEuropean child & adolescent psychiatry2018
Adolescents at ultra-high risk of psychosis in Italian neuropsychiatry services: prevalence, psychopathology and transition rate.
Article in European child & adolescent psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Sexual Dysfunctions and Problematic Sexuality in Personality Disorders and Pathological Personality Traits: A Systematic Review.Current psychiatry reports · 2023Pooled it
- Basic symptoms of psychosis-from historical foundations to current evidence.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2026Review
- Structural and Functional Neuroimaging Biomarkers as Predictors of Psychosis Conversion in Ultra-High Risk Individuals: A Systematic Review.Brain sciences · 2026Review
- Annual Research Review: Psychosis in children and adolescents: key updates from the past 2 decades on psychotic disorders, psychotic experiences, and psychosis risk.Journal of child psychology and psychiatry, and allied disciplines · 2025Review
- Multi-domain destructuring in the early phases of psychosis: a multicentric phenomenological and psychometric case-control study.Frontiers in behavioral neuroscience · 2025Article
- Network analysis of inflammation and symptoms in recent onset schizophrenia and the influence of minocycline during a clinical trial.Translational psychiatry · 2023Article
- Neurocognition and functioning in adolescents at clinical high risk for psychosis.Child and adolescent psychiatry and mental health · 2023Article
- Depressive Features in Individuals with First Episode Psychosis: Psychopathological and Treatment Considerations from A 2-Year Follow-Up Study.Clinical neuropsychiatry · 2023Article
- Negative symptoms in first episode schizophrenia: treatment response across the 2-year follow-up of the "Parma Early Psychosis" program.European archives of psychiatry and clinical neuroscience · 2022Article
- Hallucinations in the Child and Adolescent "Ultra-High Risk" population: A Systematic Review.Schizophrenia bulletin open · 2022Review
- Toward Generalizable and Transdiagnostic Tools for Psychosis Prediction: An Independent Validation and Improvement of the NAPLS-2 Risk Calculator in the Multisite PRONIA Cohort.Biological psychiatry · 2021Article
- Negative symptom configuration in patients with first episode affective psychosis: findings from the 1-year follow-up of the "Parma Early Psychosis" program.Acta bio-medica : Atenei Parmensis · 2021Article
- What happened to the concept of adolescence crisis?European child & adolescent psychiatry · 2020Article
- Subjective experience of social cognition in adolescents at ultra-high risk of psychosis: findings from a 24-month follow-up study.European child & adolescent psychiatry · 2020Article
- Telepsychotherapy with Youth at Clinical High Risk for Psychosis: Clinical Issues and Best Practices during the COVID-19 Pandemic.Journal of psychotherapy integration · 2020Article
- Clinical profile, conversion rate, and suicidal thinking and behaviour in children and adolescents at ultra-high risk for psychosis: a theoretical perspective.Research in psychotherapy (Milano) · 2020Article
- Anhedonia in adolescents at ultra-high risk (UHR) of psychosis: findings from a 1-year longitudinal study.European archives of psychiatry and clinical neuroscience · 2020Article
- Familiarity for Serious Mental Illness in Help-Seeking Adolescents at Clinical High Risk of Psychosis.Frontiers in psychiatry · 2020Article
- Spanish validation of the self-evaluation of negative symptoms scale SNS in an adolescent population.BMC psychiatry · 2019Article
- Clinical high risk for psychosis in childhood and adolescence: findings from the 2-year follow-up of the ReARMS project.European child & adolescent psychiatry · 2019Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies in adolescents on ultra-high risk (UHR) and basic symptoms (BS) criteria for psychosis prediction are scarce. In Italy, early interventions in psychosis are less widespread than in other European countries. In the present study, we (1) assessed the clinical relevance of a UHR diagnosis [according to the comprehensive assessment of at-risk mental states (CAARMS) criteria] to promote the implementation of specific services for UHR adolescents into the Italian health care system; (2) described severity of positive, negative, general, and basic symptoms in UHR adolescents compared to adolescents with first-episode psychosis (FEP) and non-UHR adolescents (i.e., individuals who did not meet CAARMS criteria for UHR or FEP); and (3) investigated the predictive validity of UHR criteria in relation to BS criteria. Seventy-nine adolescents (aged 13-18 years) were assessed with the CAARMS, the positive and negative syndrome scale (PANSS), and the schizophrenia proneness instrument, child and youth version (SPI-CY). Both UHR (n = 25) and FEP (n = 11) had significantly higher PANSS subscale scores compared to non-UHR (n = 43). UHR had significantly lower PANSS-positive symptom scores than FEP, but similar global functioning and PANSS-negative symptoms and general psychopathology scores. Compared to non-UHR, both FEP and UHR had more severe thought and perception BS disturbances, and significantly more often met BS criteria. After 12 months, 2 of 20 (10%) UHR had transitioned to psychosis. They also met both BS criteria. Given the uncertain outcome of UHR adolescents, future research is needed to determine whether the combined assessment of BS with UHR symptoms can improve the accuracy of psychosis prediction in adolescence.
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