ArticleSpinal cord2018
Magnetic resonance imaging features of dogs with incomplete recovery after acute, severe spinal cord injury.
Article in Spinal cord, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- A case series of 37 surgically managed, paraplegic, deep pain negative French bulldogs, with thoracolumbar intervertebral disc extrusion, from two English referral centres.Veterinary record open · 2023Article
- Comparison of Imaging Methods and Population Pattern in Dogs with Spinal Diseases in Three Periods between 2005 and 2022: A Retrospective Study.Veterinary sciences · 2023Article
- Significance of intramedullary T2Frontiers in veterinary science · 2023Article
- Clinical, magnetic resonance imaging, surgical features and comparison of surgically treated intervertebral disc extrusion in French bulldogs.Frontiers in veterinary science · 2023Article
- Early Locomotor Training in Tetraplegic Post-Surgical Dogs with Cervical Intervertebral Disc Disease.Animals : an open access journal from MDPI · 2022Article
- Transplantation of encapsulated autologous olfactory ensheathing cell populations expressing chondroitinase for spinal cord injury: A safety and feasibility study in companion dogs.Journal of tissue engineering and regenerative medicine · 2022Article
- ACVIM consensus statement on diagnosis and management of acute canine thoracolumbar intervertebral disc extrusion.Journal of veterinary internal medicine · 2022Article
- A Controlled Clinical Study of Intensive Neurorehabilitation in Post-Surgical Dogs with Severe Acute Intervertebral Disc Extrusion.Animals : an open access journal from MDPI · 2021Article
- Treatment of Chronic Spinal Cord Injury in Dogs Using Amniotic Membrane-Derived Stem Cells: Preliminary Results.Stem cells and cloning : advances and applications · 2021Article
- A Comparison Between Body Weight-Supported Treadmill Training and Conventional Over-Ground Training in Dogs With Incomplete Spinal Cord Injury.Frontiers in veterinary science · 2021Article
- Association between anesthesia duration and outcome in dogs with surgically treated acute severe spinal cord injury caused by thoracolumbar intervertebral disk herniation.Journal of veterinary internal medicine · 2020Article
- Ambulation in Dogs With Absent Pain Perception After Acute Thoracolumbar Spinal Cord Injury.Frontiers in veterinary science · 2020Review
- Predictors of Response to 4-Aminopyridine in Chronic Canine Spinal Cord Injury.Journal of neurotrauma · 2019Article
- Canine Snake-Eye Myelopathy: Clinical, Magnetic Resonance Imaging, and Pathologic Findings in Four Cases.Frontiers in veterinary science · 2019Article
- Diffusion Tensor Imaging in Diagnosis of Post-Traumatic Syringomyelia in Spinal Cord Injury in Rats.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
STUDY
designRetrospective case series.
objectivesDescribe the magnetic resonance imaging (MRI) features of dogs chronically impaired after severe spinal cord injury (SCI) and investigate associations between imaging variables and residual motor function.
settingUnited States of America.
methodsThoracolumbar MRI from dogs with incomplete recovery months to years after clinically complete (paralysis with loss of pain perception) thoracolumbar SCI were reviewed. Lesion features were described and quantified. Gait was quantified using an ordinal, open field scale (OFS). Associations between imaging features and gait scores, duration of injury (DOI), or SCI treatment were determined.
resultsThirty-five dogs were included. Median OFS was 2 (0-6), median DOI was 13 months (3-83), and intervertebral disk herniation was the most common diagnosis (n = 27). Myelomalacia was the most common qualitative feature followed by cystic change; syringomyelia and fibrosis were uncommon. Lesion length corrected to L2 length (LL:L2) was variable (median LL:L2 = 3.5 (1.34-11.54)). Twenty-nine dogs had 100% maximum cross-sectional spinal cord compromise (MSCC) at the lesion epicenter and the length of 100% compromised area varied widely (median length 100% MSCC:L2 = 1.29 (0.39-7.64)). Length 100% MSCC:L2 was associated with OFS (p = 0.012). OFS was not associated with any qualitative features. DOI or treatment type were not associated with imaging features or lesion quantification.
conclusionsLesion characteristics on MRI in dogs with incomplete recovery after severe SCI were established. Length of 100% MSCC was associated with hind limb motor function. Findings demonstrate a spectrum of injury severity on MRI among severely affected dogs, which is related to functional status.
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