ArticleScientific reports2017
Photosensing and Thermosensing by Phytochrome B Require Both Proximal and Distal Allosteric Features within the Dimeric Photoreceptor.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 45 citations in OpenAlex.
- Hypsochromic shift in phytochrome C Pr absorption complements phytochrome B-mediated inhibition of hypocotyl elongation.The Plant journal : for cell and molecular biology · 2026Article
- Twenty-five years of photobodies: formation, composition, and the 2-compartment logic of phytochrome B signaling.Plant physiology · 2026Review
- Pr and Pfr structures of plant phytochrome A.Nature communications · 2025Article
- Application of Multi-Omics Technologies to the Study of Phytochromes in Plants.Antioxidants (Basel, Switzerland) · 2024Review
- Structural insights into plant phytochrome A as a highly sensitized photoreceptor.Cell research · 2023Article
- Plant phytochrome A in the Pr state assembles as an asymmetric dimer.Cell research · 2023Article
- The structure of Arabidopsis phytochrome A reveals topological and functional diversification among the plant photoreceptor isoforms.Nature plants · 2023Article
- Article
- Engineering Light-Control in Biology.Frontiers in bioengineering and biotechnology · 2022Review
- Phytochrome Signaling Networks.Annual review of plant biology · 2021Review
- Differing biophysical properties underpin the unique signaling potentials within the plant phytochrome photoreceptor families.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Red light-induced structure changes in phytochrome A from Pisum sativum.Scientific reports · 2021Article
- Cryo-Electron Microscopy ofFrontiers in plant science · 2021Article
- CreLite: An optogenetically controlled Cre/loxP system using red light.Developmental dynamics : an official publication of the American Association of Anatomists · 2020Article
- Lights, cytoskeleton, action: Optogenetic control of cell dynamics.Current opinion in cell biology · 2020Review
- Near-Infrared Markers based on Bacterial Phytochromes with Phycocyanobilin as a Chromophore.International journal of molecular sciences · 2019Article
- Molecular mechanisms underlying phytochrome-controlled morphogenesis in plants.Nature communications · 2019Review
- Dark, Light, and Temperature: Key Players in Plant Morphogenesis.Plant physiology · 2019Article
- Physicochemical modeling of the phytochrome-mediated photothermal sensing.Scientific reports · 2019Article
- Plant Phytochromes and their Phosphorylation.International journal of molecular sciences · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
Phytochromes (Phys) encompass a diverse collection of bilin-containing photoreceptors that help plants and microorganisms perceive light through photointerconversion between red light (Pr) and far-red light (Pfr)-absorbing states. In addition, Pfr reverts thermally back to Pr via a highly enthalpic process that enables temperature sensation in plants and possibly other organisms. Through domain analysis of the Arabidopsis PhyB isoform assembled recombinantly, coupled with measurements of solution size, photoconversion, and thermal reversion, we identified both proximal and distal features that influence all three metrics. Included are the downstream C-terminal histidine kinase-related domain known to promote dimerization and a conserved patch just upstream of an N-terminal Period/Arnt/Sim (PAS) domain, which upon removal dramatically accelerates thermal reversion. We also discovered that the nature of the bilin strongly influences Pfr stability. Whereas incorporation of the native bilin phytochromobilin into PhyB confers robust Pfr → Pr thermal reversion, that assembled with the cyanobacterial version phycocyanobilin, often used for optogenetics, has a dramatically stabilized Pfr state. Taken together, we conclude that Pfr acquisition and stability are impacted by a collection of opposing allosteric features that inhibit or promote photoconversion and reversion of Pfr back to Pr, thus allowing Phys to dynamically measure light, temperature, and possibly time.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.