Evidence map›Paper›PMID 29057920›Full record

ArticleScientific reports2017

Halogenated Chrysins Inhibit Dengue and Zika Virus Infectivity.

Aphinya Suroengrit, Wanchalerm Yuttithamnon, Pimsiri Srivarangkul, Saran Pankaew, Krongkan Kingkaew, Warinthorn Chavasiri, Siwaporn Boonyasuppayakorn

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Natural products as Zika antivirals.Medicinal research reviews · 2022
    Review
  10. Article
  11. Review
  12. Review
  13. Flavonoids as Molecules With Anti-Frontiers in microbiology · 2021
    Review
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aphinya SuroengritGraduate Program, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Wanchalerm YuttithamnonDepartment of Biology, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Pimsiri SrivarangkulDepartment of Biology, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Saran PankaewDepartment of Biology, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Krongkan KingkaewDepartment of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Warinthorn ChavasiriDepartment of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Siwaporn BoonyasuppayakornChula-Vaccine Research Center, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand. siwaporn.b@chula.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue virus infection is a global threat for which no specific treatment has not been established. Previous reports suggested chrysin and flavanone derivatives were potential flaviviral inhibitors. Here, we reported two halogenated chrysins, abbreviated FV13 and FV14, were highly potent against DENV1-4 and ZIKV infectivities with the FV13 EC

Indexed as

AnimalsAntiviral AgentsCell LineCell SurvivalChlorocebus aethiopsDengueDengue VirusDose-Response Relationship, DrugFlavonesHumansMacaca mulattaMolecular StructureZika VirusZika Virus InfectionAntiviral AgentsFlavones

Identifiers

PMID29057920
PMCPMC5651866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.