ArticleScientific reports2017
Ultrasound localization microscopy to image and assess microvasculature in a rat kidney.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05754814 (SUper-Resolution Ultrasound Imaging of Erythrocytes), which is not on this map. Cited by 70 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
SUper-Resolution Ultrasound Imaging of Erythrocytes (SURE) in Normal and Malignant Lymph Nodes
Who cites it
70 citing papers in PubMed, 164 citations in OpenAlex.
- Endothelial Continuum and Capillary Specialization in Pulmonary Vascular Development.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- Prospective Pilot Study of Ultrasound Resolution Microscopy Imaging (URM) for Differentiating Benign and Malignant Breast Lesions: A Quantitative Microvascular Parameter Analysis.Diagnostics (Basel, Switzerland) · 2026Article
- Towards reduced ultrasound localization microscopy acquisition times by uncoupling a bi-disperse microbubble population.The ultrasound journal · 2026Article
- Application of ultrasound localization microscopy in the diagnosis and treatment of kidney diseases.Journal of ultrasound · 2026Review
- EBDE clearing: A strategy for simultaneous 3D visualization and quantitative analysis of both renal arteries and glomeruli.Theranostics · 2026Article
- Ultrasound Imaging.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026Review
- Principles of Doppler ultrasound and emerging blood flow imaging.Ultrasonography (Seoul, Korea) · 2025Article
- Ultrafast ultrasound localization microscopy for differential diagnosis of reactive hyperplasia and metastatic cervical lymph nodes: a pilot study.Quantitative imaging in medicine and surgery · 2025Article
- Mapping the arterial vascular network in an intact human kidney using hierarchical phase-contrast tomography.Npj imaging · 2025Article
- Differentiation of benign and malignant breast lesions by ultrasound localization microscopy.Insights into imaging · 2025Article
- Label-Free Dual-Modal Photoacoustic/Ultrasound Localization Imaging for Studying Acute Kidney Injury.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Microvascular blood flow ultrasound imaging with microbubble-based H-Scan technology.Medical & biological engineering & computing · 2025Article
- Transcranial brain-wide functional ultrasound and ultrasound localization microscopy in mice using multi-array probes.Scientific reports · 2025Article
- OptimizingPhysics in medicine and biology · 2025Article
- Ultrasound localization microscopy in the diagnosis of breast tumors and prediction of relevant histologic biomarkers associated with prognosis in humans: the protocol for a prospective, multicenter study.BMC medical imaging · 2025Article
- Velocity-Constraint Kalman Filtering for Enhanced Bubble Tracking in Motion-Compensated Ultrasound Localization Microscopy.Research (Washington, D.C.) · 2025Article
- 3D ultrasound localization microscopy of the nonhuman primate brain.EBioMedicine · 2025Article
- Article
- Innovative Approaches to Brain Cancer: The Use of Magnetic Resonance-guided Focused Ultrasound in Glioma Therapy.Cancers · 2024Review
- Non-invasive 4D transcranial functional ultrasound and ultrasound localization microscopy for multimodal imaging of neurovascular response.Scientific reports · 2024Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The recent development of ultrasound localization microscopy, where individual microbubbles (contrast agents) are detected and tracked within the vasculature, provides new opportunities for imaging the vasculature of entire organs with a spatial resolution below the diffraction limit. In stationary tissue, recent studies have demonstrated a theoretical resolution on the order of microns. In this work, single microbubbles were localized in vivo in a rat kidney using a dedicated high frame rate imaging sequence. Organ motion was tracked by assuming rigid motion (translation and rotation) and appropriate correction was applied. In contrast to previous work, coherence-based non-linear phase inversion processing was used to reject tissue echoes while maintaining echoes from very slowly moving microbubbles. Blood velocity in the small vessels was estimated by tracking microbubbles, demonstrating the potential of this technique to improve vascular characterization. Previous optical studies of microbubbles in vessels of approximately 20 microns have shown that expansion is constrained, suggesting that microbubble echoes would be difficult to detect in such regions. We therefore utilized the echoes from individual MBs as microscopic sensors of slow flow associated with such vessels and demonstrate that highly correlated, wideband echoes are detected from individual microbubbles in vessels with flow rates below 2 mm/s.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.