Evidence map›Paper›PMID 29057809›Full record

ArticleMolecules (Basel, Switzerland)2017

Hepatoprotective Effects of Kaempferol-3-O-α-l-Arabinopyranosyl-7-O-α-l-Rhamnopyranoside on d-Galactosamine and Lipopolysaccharide Caused Hepatic Failure in Mice.

Lin Dong, Lei Yin, Hongfeng Quan, Yuankui Chu, Jincai Lu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Hepatoprotective Effect of Kaempferol-A Review.Molecules (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Total Flavonoids ofOxidative medicine and cellular longevity · 2021
    Article
  7. Article
  8. Supercritical CO₂ Fluid Extraction ofMolecules (Basel, Switzerland) · 2019
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lin DongSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China. fanwuz716485@126.com.
Lei YinSchool of Pharmacy, Ningxia Medical University, Yinchuan 750004, China. tangjuxian957@163.com.
Hongfeng QuanSchool of Pharmacy, Ningxia Medical University, Yinchuan 750004, China. cisheng31352@yeah.net.
Yuankui ChuDepartment of Laboratory Medicine, General Hospital of Ningxia Medical University, Ningxia Medical University, Yinchuan 750004, China. lingshugc149179@126.com.
Jincai LuSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China. jincailu@yeah.net.
Ningxia Medical University · CNShenyang Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fulminant hepatic failure (FHF), associated with high mortality, is characterized by extensive death of hepatocytes and hepatic dysfunction. There is no effective treatment for FHF. Several studies have indicated that flavonoids can protect the liver from different factor-induced injury. Previously, we found that the extracts of

Indexed as

Alanine TransaminaseAnimalsApoptosisAspartate AminotransferasesElaeagnaceaeGalactosamineGene Expression RegulationGlycosidesKaempferolsLipopolysaccharidesLiverLiver Failure, AcuteMalondialdehydeMiceNF-kappa BPlant ExtractsAlanine TransaminaseAspartate AminotransferasesGalactosamineGlycosideskaempferol-7-O-alpha-L-rhamnopyranosideKaempferolsLipopolysaccharidesMalondialdehydeNF-kappa BPlant ExtractsReactive Oxygen SpeciesTlr4 protein, mouseToll-Like Receptor 4acute hepatic failureapoptosisElaeagnus mollis Dielsinflammatory responseskaempferol-3-O-α-">l-arabinopyranosyl-7-O-α-">l-rhamnopyranoside

Identifiers

PMID29057809
PMCPMC6151520
OpenAlexW2766248838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.