Evidence map›Paper›PMID 29057373›Full record

ArticleNanoImpact2017

Biokinetics of Nanomaterials: the Role of Biopersistence.

Peter Laux, Christian Riebeling, Andy M Booth, Joseph D Brain, Josephine Brunner, Cristina Cerrillo, Otto Creutzenberg, Irina Estrela-Lopis, Thomas Gebel, Gunnar Johanson and 8 more

Abstract read
In one paragraph

Article in NanoImpact, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. The Role of Metal Oxide Nanoparticles,Environmental science. Nano · 2020
    Article
  15. Article
  16. Genotoxicity of Silver Nanoparticles.Nanomaterials (Basel, Switzerland) · 2020
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Peter LauxGerman Federal Institute for Risk Assessment, Department of Chemical and Product Safety, Max-Dohrn-Strasse 8-10, 10589 Berlin, Germany.
Christian RiebelingGerman Federal Institute for Risk Assessment, Department of Chemical and Product Safety, Max-Dohrn-Strasse 8-10, 10589 Berlin, Germany.
Andy M BoothSINTEF Materials and Chemistry, Trondheim N-7465, Norway.
Joseph D BrainHarvard T. H. Chan School of Public Health, Boston, MA, USA.
Josephine BrunnerGerman Federal Institute for Risk Assessment, Department of Chemical and Product Safety, Max-Dohrn-Strasse 8-10, 10589 Berlin, Germany.
Cristina CerrilloIK4-Tekniker, Tribology Unit, Iñaki Goenaga 5, 20600 Eibar, Spain.
Otto CreutzenbergFraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Department of Inhalation Toxicology, Nikolai Fuchs Strasse 1, 30625 Hannover, Germany.
Irina Estrela-LopisInstitute of Medical Physics & Biophysics, Leipzig University, Härtelstraße 16, 04107 Leipzig, Germany.
Thomas GebelGerman Federal Institute for Occupational Safety and Health (BAuA), Friedrich-Henkel-Weg 1-25, 44149 Dortmund, Germany.
Gunnar JohansonInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Harald JungnickelGerman Federal Institute for Risk Assessment, Department of Chemical and Product Safety, Max-Dohrn-Strasse 8-10, 10589 Berlin, Germany.
Heiko KockFraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Department of Inhalation Toxicology, Nikolai Fuchs Strasse 1, 30625 Hannover, Germany.
Jutta TentschertGerman Federal Institute for Risk Assessment, Department of Chemical and Product Safety, Max-Dohrn-Strasse 8-10, 10589 Berlin, Germany.
Ahmed TliliDepartment of Environmental Toxicology, Eawag, Swiss Federal Institute of Aquatic Science and Technology, Dübendorf, Switzerland.
Andreas SchäfferInstitute for Environmental Research, RWTH Aachen University, Aachen, Germany.
Adriënne J A M SipsNational Institute for Public Health & the Environment (RIVM), Bilthoven, The Netherlands.
Robert A YokelPharmaceutical Sciences, University of Kentucky, Lexington, Kentucky, USA.
Andreas LuchGerman Federal Institute for Risk Assessment, Department of Chemical and Product Safety, Max-Dohrn-Strasse 8-10, 10589 Berlin, Germany.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
NIEHS NIH HHS P30 ES000002
6 · The paper itself

Abstract

Nanotechnology risk management strategies and environmental regulations continue to rely on hazard and exposure assessment protocols developed for bulk materials, including larger size particles, while commercial application of nanomaterials (NMs) increases. In order to support and corroborate risk assessment of NMs for workers, consumers, and the environment it is crucial to establish the impact of biopersistence of NMs at realistic doses. In the future, such data will allow a more refined future categorization of NMs. Despite many experiments on NM characterization and numerous

Indexed as

Biokineticsdosimetryextrapulmonary organsgranular biopersistent particle (GBP)inhalation

Identifiers

PMID29057373
PMCPMC5645051

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.