ArticleJournal of spine surgery (Hong Kong)2017
Composite PEEK/Carbon fiber implants can increase the effectiveness of radiotherapy in the management of spine tumors.
Article in Journal of spine surgery (Hong Kong), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 53 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 4 syntheses or guidelines pooled it, 106 citations in OpenAlex.
- Carbon fiber-PEEK pedicle screw instrumentation in spinal oncology: a retrospective case series, systematic review of the literature, and cost-effectiveness analysis.Journal of neuro-oncology · 2026Pooled it
- Carbon fiber-reinforced polyetheretherketone implants versus titanium implants for spinal tumors: a systematic review and meta-analysis.Journal of neuro-oncology · 2026Pooled it
- Clinical performance of implanted devices used in surgical treatment of patients with spinal tumors: a systematic review.BMC musculoskeletal disorders · 2024Pooled it
- Carbon-fibre plates for traumatic and (impending) pathological fracture fixation: Where do we stand? A systematic review.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2023Pooled it
- Carbon fiber-reinforced peek versus titanium implants for the surgical treatment of spinal metastases: Evaluation of local disease control and quality of life.Journal of bone oncology · 2026Article
- Vertebral metastatic disease: A paradigm shift.Neuro-oncology advances · 2026Review
- Robot-Assisted Placement of Thoracic Carbon-Fiber-Reinforced Polyetheretherketone (CFR-Peek) Pedicle Screws in the Cervical Spine for Giant Cell Tumor: Technical Note.Bioengineering (Basel, Switzerland) · 2026Article
- Carbon fiber-reinforced polyetheretherketone spinal instrumentation in pediatric spinal tumors: report of two cases and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Review
- Use of carbon fiber-reinforced PEEK cages in spinal oncology patients: An institutional experience with emphasis on surgical, complication and imaging characteristics.Acta neurochirurgica · 2025Article
- Carbon fibre PEEK versus titanium cephalomedullary nails for management of oncological lesions of the femur: a retrospective cohort study.BMC musculoskeletal disorders · 2025Article
- The Radiologists' Guide to Spinal Separation Surgery: What Does the Surgeon Want to Know?Diseases (Basel, Switzerland) · 2025Review
- Article
- Local Control After Adjuvant Radiosurgery for Spinal Metastasis Treated With Decompression and Posterior Segmental Stabilization: A Comparison Between Carbon Fiber/Polyetheretherketone-Based and Metallic Implants.Advances in radiation oncology · 2025Article
- Enhanced strength and durability of long fiber type carbon fiber reinforced plastic rods over titanium alloy rods for spinal fixation.North American Spine Society journal · 2025Article
- En bloc resection, including the cord for tumor-free margin, in a multilevel osteosarcoma of the spine: 20-year disease-free survival. Illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Carbon-based pedicle screw fixation for lumbar fusion for degenerative pathologies in a cancer patient requiring radiotherapy.Journal of surgical case reports · 2025Article
- Radiotherapy and surgery: can this combination be further optimized for patients with metastatic spine disease?The oncologist · 2025Review
- Impact of instrumentation material on local recurrence: a case-matched series using carbon fiber-PEEK vs. titanium.Journal of neuro-oncology · 2025Article
- Role of Posterior Carbon Fiber Implants in Spine Tumor Surgery.Global spine journal · 2025Article
- Carbon Fiber Reinforced Hybrid Polyaryl-Ether-Ether-Ketone (PEEK) Spinal Fixation System: Technical Features and Preliminary Clinical Trial.Indian journal of orthopaedics · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCombination of surgery and radiotherapy in the treatment of primary spine tumour can be indicated in some cases where a satisfactory oncological margin cannot be achieved. The presence of metal hardware has always limited post-operative radiotherapy due to the scattering effects of ionizing radiation or particles. The use of a fixation system (including rods and screw) fully made in PEEK embedded Carbon fiber (CFR-PEEK) could make easier and more effective the post-operative radiotherapy as it is radiolucent and does not interfere with ionizing radiation and accelerated particles.
methodsAn ambispective study was performed on the first 22 consecutive primary tumor patients, who underwent spinal surgery including a composite CFR-PEEK fixation system. Oncologic surgery was palliative decompression and fixation in 3 cases; tumor excision in 15; en bloc resection in 4. The incidence of complications (intra- and postoperative), local control (LC) and local recurrence (LR), and changes in neurological status were considered.
resultsOnly one intraoperative screw breakage occurred and one case of loosening of sacral screws were found at 12 months in one patient. No rod breakage, neither any screw/rod disconnection was found. Post-operative RT has been performed in 19 patients. The overall number of progression of the tumour or LR was 7. The actuarial rate of LR or progression of the tumour, calculated according to the Kaplan-Meier method, was 17.6% at 12 months.
conclusionsThe CFR-PEEK fixation system is comparable to standard titanium system in term of intraoperative complications, stability at weight bearing and at functional recovery. Thanks to radiolucency CFR-PEEK stabilization devices are more suitable in patients eligible for RT: the absence of image artifacts together with significantly less dose perturbation improve the treatment accuracy. Moreover the radiolucency is useful in the follow-up of patients thus allowing early detection of LR.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.