Evidence map›Paper›PMID 29057325›Full record

ArticleScience advances2017

Comprehensive vaccine design for commensal disease progression.

Charles H Jones, Guojian Zhang, Roozbeh Nayerhoda, Marie Beitelshees, Andrew Hill, Pooya Rostami, Yi Li, Bruce A Davidson, Paul Knight, Blaine A Pfeifer

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  3. Influence of glycan structure on the colonization ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Review
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  16. Human Vaccines & Immunotherapeutics: News.Human vaccines & immunotherapeutics · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Charles H JonesAbcombi Biosciences Inc., Buffalo, NY 14228, USA.
Guojian ZhangDepartment of Chemical and Biological Engineering, University at Buffalo, State University of New York, Buffalo, NY 14260, USA.
Roozbeh NayerhodaDepartment of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, NY 14260, USA.
Marie BeitelsheesDepartment of Chemical and Biological Engineering, University at Buffalo, State University of New York, Buffalo, NY 14260, USA.
Andrew HillAbcombi Biosciences Inc., Buffalo, NY 14228, USA.ORCID 0000-0002-1784-0829
Pooya RostamiNew York University Langone Medical Center, Brooklyn, NY 11229, USA.ORCID 0000-0002-6766-0762
Yi LiDepartment of Chemical and Biological Engineering, University at Buffalo, State University of New York, Buffalo, NY 14260, USA.
Bruce A DavidsonDepartment of Anesthesiology, University at Buffalo, State University of New York, Buffalo, NY 14214, USA.ORCID 0000-0001-8223-1870
Paul KnightDepartment of Anesthesiology, University at Buffalo, State University of New York, Buffalo, NY 14214, USA.ORCID 0000-0002-9201-3305
Blaine A PfeiferDepartment of Chemical and Biological Engineering, University at Buffalo, State University of New York, Buffalo, NY 14260, USA.ORCID 0000-0002-9338-2794
University at Buffalo, State University of New York · USAbcombi Biosciences (United States) · USNYU Langone Health · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
A Hybrid Bio-synthetic Vector Designed to Elicit Directed in vivo Immune ResponseR21AI117309 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI PFEIFER, BLAINE A. · 2016 to 2017
$435k
A Hybrid Biomaterial-biological Vector for Antigen Presenting Cell Gene DeliveryR03AI088485 · NIAID · TUFTS UNIVERSITY MEDFORD · PI PFEIFER, BLAINE A. · 2010 to 2011
$145k
NCATS NIH HHS UL1 TR001412NIAID NIH HHS R03 AI088485NIAID NIH HHS R21 AI117309
6 · The paper itself

Abstract

Commensal organisms with the potential to cause disease pose a challenge in developing treatment options. Using the example featured in this study, pneumococcal disease begins with

Indexed as

BioengineeringVaccinesAnimalsAntigensBiotechnologyDisease ProgressionFemaleHumansImmunity, InnateImmunogenicity, VaccineMicePneumococcal InfectionsPneumococcal VaccinesPrevalenceSerogroupVaccinationAntigensPneumococcal VaccinesVaccines

Identifiers

PMID29057325
PMCPMC5647123
OpenAlexW2766920391

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.