ArticleNeurophotonics2018
Using prerecorded hemodynamic response functions in detecting prefrontal pain response: a functional near-infrared spectroscopy study.
Article in Neurophotonics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 28 citations in OpenAlex.
- Exploring Cognitive Load and Relative Neural Efficiency in Aging: : Preliminary Insights from fNIRS and the SLUMS Assessment.Delaware journal of public health · 2026Article
- Connectivity-Based Pain Recognition from fNIRS: Parsimonious Subject-Independent Classification.Sensors (Basel, Switzerland) · 2026Article
- Advancing pain assessment in Alzheimer's disease and related dementias: Functional near-infrared spectroscopy for investigating brain activity.British journal of pain · 2026Article
- Article
- Functional near-infrared spectroscopy (fNIRS) detects brain changes for apathy and pain in patients with Alzheimer's disease and related dementias: An exploratory study.Neuroimage. Reports · 2025Article
- Evaluation of pressure-induced pain in patients with disorders of consciousness based on functional near infrared spectroscopy.Frontiers in neurology · 2025Article
- Global trends and performances of infrared imaging technology studies on acupuncture: a bibliometric analysis.Frontiers in neuroscience · 2024Review
- Machines, mathematics, and modules: the potential to provide real-time metrics for pain under anesthesia.Neurophotonics · 2024Article
- Cerebral cortical hemodynamic metrics to aid in assessing pain levels? A pilot study of functional near-infrared spectroscopy.Frontiers in neuroscience · 2023Article
- Self-administered transcranial direct current stimulation treatment of knee osteoarthritis alters pain-related fNIRS connectivity networks.Neurophotonics · 2023Article
- A study based on functional near-infrared spectroscopy: Cortical responses to music interventions in patients with myofascial pain syndrome.Frontiers in human neuroscience · 2023Article
- Age-Related Differences in Stepping Reactions to a Balance Perturbation: A Functional Near-Infrared Spectroscopy and Surface Electromyography Study.Brain sciences · 2022Article
- Neuroimaging Assessment of Pain.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022Review
- Effect of the Application of Virtual Reality on Pain Reduction and Cerebral Blood Flow in Robot-Assisted Gait Training in Burn Patients.Journal of clinical medicine · 2022Article
- Effect of spinal anesthesia-induced deafferentation on pain processing in healthy male volunteers: A task-related fMRI study.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- fNIRS brain measures of ongoing nociception during surgical incisions under anesthesia.Neurophotonics · 2022Article
- Measuring "pain load" during general anesthesia.Cerebral cortex communications · 2022Article
- Review
- Rhythmic Change of Cortical Hemodynamic Signals Associated with Ongoing Nociception in Awake and Anesthetized Individuals: An Exploratory Functional Near Infrared Spectroscopy Study.Anesthesiology · 2021Article
- Subliminal (latent) processing of pain and its evolution to conscious awareness.Neuroscience and biobehavioral reviews · 2018Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
Currently, there is no method for providing a nonverbal objective assessment of pain. Recent work using functional near-infrared spectroscopy (fNIRS) has revealed its potential for objective measures. We conducted two fNIRS scans separated by 30 min and measured the hemodynamic response to the electrical noxious and innocuous stimuli over the anterior prefrontal cortex (aPFC) in 14 subjects. Based on the estimated hemodynamic response functions (HRFs), we first evaluated the test-retest reliability of using fNIRS in measuring the pain response over the aPFC. We then proposed a general linear model (GLM)-based detection model that employs the subject-specific HRFs from the first scan to detect the pain response in the second scan. Our results indicate that fNIRS has a reasonable reliability in detecting the hemodynamic changes associated with noxious events, especially in the medial portion of the aPFC. Compared with a standard HRF with a fixed shape, including the subject-specific HRFs in the GLM allows for a significant improvement in the detection sensitivity of aPFC pain response. This study supports the potential application of individualized analysis in using fNIRS and provides a robust model to perform objective determination of pain perception.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.