Evidence map›Paper›PMID 29057080›Full record

ArticleJournal of virus eradication2017

The role of miR-29a in HIV-1 replication and latency.

Giacomo Frattari, Lars Aagaard, Paul W Denton

Abstract readEditorial
In one paragraph

Article in Journal of virus eradication, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. A Systematic Review of miR-29 in Cancer.Molecular therapy oncolytics · 2019
    Review
  10. Antiretroviral drug-S for a possible HIV elimination.International journal of physiology, pathophysiology and pharmacology · 2019
    Article
  11. Barriers for HIV Cure: The Latent Reservoir.AIDS research and human retroviruses · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giacomo FrattariDepartment of Infectious Diseases, Aarhus University Hospital Skejby, Aarhus, Denmark.
Lars AagaardDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Paul W Denton

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of an effective HIV-1 eradication strategy relies upon a clear understanding of the cellular mechanisms involved in HIV-1 latency. Among such cellular processes, microRNA activities affect HIV-1 production by regulating viral transcripts as well as host cell HIV-1 dependency factors. miR-29a stands apart from other relevant microRNAs as a potential therapeutic target in HIV-1 eradication.

Indexed as

shock and kill, lock and block, microRNAs, HIV eradication

Identifiers

PMID29057080
PMCPMC5632543

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.