Evidence map›Paper›PMID 29057054›Full record

ArticleACS medicinal chemistry letters2017

Discovery of Novel 5-(Piperazine-1-carbonyl)pyridin-2(1

Ryo Mizojiri, Daisuke Nakata, Yoshihiko Satoh, Daisuke Morishita, Sachio Shibata, Misa Iwatani-Yoshihara, Yohei Kosugi, Mai Kosaka, Junpei Takeda, Shigekazu Sasaki and 7 more

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ryo MizojiriResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Daisuke NakataResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Yoshihiko SatohResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Daisuke MorishitaResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Sachio ShibataResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Misa Iwatani-YoshiharaResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Yohei KosugiResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Mai KosakaResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Junpei TakedaResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Shigekazu SasakiResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Kazuaki TakamiResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Koichiro FukudaResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Masahiro KamauraResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Shinobu SasakiResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Ryosuke AraiResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Douglas R CaryResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.
Yasuhiro ImaedaResearch, Takeda Pharmaceutical Company Ltd., Fujisawa, Kanagawa 251-8555, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Starting from our previous eIF4A3-selective inhibitor

Indexed as

Eukaryotic initiation factor 4A3 (eIF4A3) inhibitormetabolic stabilityP-gp substratepyridin-2(1H)-one derivativeRNA helicasesolubility

Identifiers

PMID29057054
PMCPMC5642020

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.