ArticleJournal of geriatric cardiology : JGC2017
The serum anion gap is associated with disease severity and all-cause mortality in coronary artery disease.
Article in Journal of geriatric cardiology : JGC, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Association between serum anion gap and 28-day mortality among patients admitted to the hospital with aortic dissection: a retrospective cohort study with the MIMIC-IV database.Journal of thoracic disease · 2026Article
- Association between enteral nutrition timing and postoperative anion gap trajectory in cardiac surgery ICU patients: a retrospective study based on the MIMIC-IV database.Journal of cardiothoracic surgery · 2026Article
- Effects of statins on serum sCD40, sCD146 and PAPP-An in patients with coronary heart disease.Journal of medical biochemistry · 2025Article
- The prognostic value of pulmonary hypertension in intensive care unit patients from Beth Israel Deaconess Medical Center (BIDMC).Journal of cardiothoracic surgery · 2025Article
- Observational
- Association between anion gap and postoperative delirium in patients undergoing open heart surgery.Frontiers in cardiovascular medicine · 2025Article
- Association between Albumin-Corrected Anion Gap and Mortality in Patients with Cardiogenic Shock.Reviews in cardiovascular medicine · 2024Article
- Association between anion gap and the 30-day mortality of patients with ventilator-associated pneumonia: a study of the MIMIC-III database.Journal of thoracic disease · 2024Article
- Unveiling the hidden risks: albumin-corrected anion gap as a superior marker for cardiovascular mortality in type 2 diabetes: insights from a nationally prospective cohort study.Frontiers in endocrinology · 2024Article
- Relationship between anion gap and in-hospital mortality in intensive care patients with liver failure: a retrospective propensity score matching analysis.American journal of translational research · 2024Article
- The association between serum anion gap and acute kidney injury after coronary artery bypass grafting in patients with acute coronary syndrome.BMC cardiovascular disorders · 2023Article
- A biomarker discovery of acute myocardial infarction using feature selection and machine learning.Medical & biological engineering & computing · 2023Article
- Relationship Between Albumin-Corrected Anion Gap and Mortality in Hospitalized Heart Failure Patients.Cureus · 2023Article
- Association between albumin corrected anion gap and 30-day all-cause mortality of critically ill patients with acute myocardial infarction: a retrospective analysis based on the MIMIC-IV database.BMC cardiovascular disorders · 2023Article
- Association between albumin corrected anion gap and all-cause mortality in critically ill patients with acute kidney injury: a retrospective study based on MIMIC-IV database.Renal failure · 2023Article
- Preoperative albumin corrected anion gap is associated with in-hospital and long-term mortality in patients undergoing coronary artery bypass grafting in a retrospective cohort study.Journal of thoracic disease · 2022Article
- Minding the Gap Beyond Kidney Disease: Utility of the Anion Gap in Metabolic Syndrome.Kidney360 · 2022Article
- Plasma anion gap and risk of in-hospital mortality in patients with spontaneous subarachnoid hemorrhage.Frontiers in neurology · 2022Article
- Serum Anion Gap is Associated with Risk of All-Cause Mortality in Critically Ill Patients with Acute Myocardial Infarction.International journal of general medicine · 2022Article
- Postoperative anion gap associates with short- and long-term mortality after cardiac surgery: A large-scale cohort study.Frontiers in cardiovascular medicine · 2022Article
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Authors and funding
18 authors.
Funding
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Abstract
objectiveTo evaluate the associations between the serum anion gap (AG) with the severity and prognosis of coronary artery disease (CAD).
methodsWe measured serum electrolytes in 18,115 CAD patients indicated by coronary angiography. The serum AG was calculated according to the equation: AG = Na
resultsA total of 4510 (24.9%) participants had their AG levels greater than 16 mmol/L. The serum AG was independently associated with measures of CAD severity, including more severe clinical types of CAD (
conclusionIn this large population-based study, our findings reveal a high percentage of increased serum AG in CAD. Higher AG is associated with more severe clinical types of CAD and worse cardiac function. Furthermore, the increased serum AG is an independent, significant, and strong predictor of all-cause mortality. These findings support a role for the serum AG in the risk-stratification of CAD.
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