Evidence map›Paper›PMID 29056915›Full record

ArticleFrontiers in physiology2017

Short-Duration Maximal and Long-Duration Submaximal Effort Forearm Exercise Achieve Elevations in Serum Brain-Derived Neurotrophic Factor.

Jeremy J Walsh, Robert F Bentley, Brendon J Gurd, Michael E Tschakovsky

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jeremy J WalshHuman Vascular Control Lab, School of Kinesiology and Health Studies, Queen's University, Kingston, ON, Canada.
Robert F BentleyHuman Vascular Control Lab, School of Kinesiology and Health Studies, Queen's University, Kingston, ON, Canada.
Brendon J GurdQueen's Muscle Physiology Lab, School of Kinesiology and Health Studies, Queen's University, Kingston, ON, Canada.
Michael E TschakovskyHuman Vascular Control Lab, School of Kinesiology and Health Studies, Queen's University, Kingston, ON, Canada.
Queen's University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain-derived neurotrophic factor (BDNF) is a major orchestrator of exercise-induced brain plasticity and circulating (peripheral) BDNF may have central effects. Approximately 99% of circulating BDNF is platelet-bound, and at rest ~30% of circulating platelets are stored in the spleen. Interestingly, forearm handgrip exercise significantly elevates sympathetic outflow and has been shown to induce splenic constriction, suggesting that small muscle mass exercise could stand as a viable strategy for increasing circulating BDNF; however, the BDNF response to handgrip exercise is currently unknown.

Indexed as

BDNF doseexercise intensityhandgrip exerciseneurotrophinplateletsthrombocytosis

Identifiers

PMID29056915
PMCPMC5635651
OpenAlexW2755597091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.