Evidence map›Paper›PMID 29056821›Full record

ArticleIndustrial & engineering chemistry research2015

Engineering Novel and Improved Biocatalysts by Cell Surface Display.

Mason R Smith, Eshita Khera, Fei Wen

Abstract read
In one paragraph

Article in Industrial & engineering chemistry research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Biological Upcycling of Plastics Waste.Annual review of chemical and biomolecular engineering · 2024
    Review
  8. Bacterial Membrane Vesicles for In Vitro Catalysis.Bioengineering (Basel, Switzerland) · 2023
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Regulated strategies of cold-adapted microorganisms in response to cold: a review.Environmental science and pollution research international · 2021
    Review
  15. Cell-surface engineering of yeasts for whole-cell biocatalysts.Bioprocess and biosystems engineering · 2021
    Review
  16. Review
  17. Article
  18. Article
  19. ACS synthetic biology · 2020
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mason R SmithDepartment of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States.
Eshita KheraDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States.
Fei WenDepartment of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States.

Funding

A la carte 2D artificial antigen presenting system mimicking supramolecular patterns in the natural immunological synapse for precise functional conditioning of tumor-specific T cellsR03CA191952 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEN, FEI · 2015 to 2016
$155k
NCI NIH HHS R03 CA191952
6 · The paper itself

Abstract

Biocatalysts, especially enzymes, have the ability to catalyze reactions with high product selectivity, utilize a broad range of substrates, and maintain activity at low temperature and pressure. Therefore, they represent a renewable, environmentally friendly alternative to conventional catalysts. Most current industrial-scale chemical production processes using biocatalysts employ soluble enzymes or whole cells expressing intracellular enzymes. Cell surface display systems differ by presenting heterologous enzymes extracellularly, overcoming some of the limitations associated with enzyme purification and substrate transport. Additionally, coupled with directed evolution, cell surface display is a powerful platform for engineering enzymes with enhanced properties. In this review, we will introduce the molecular and cellular principles of cell surface display and discuss how it has been applied to engineer enzymes with improved properties as well as to develop surface-engineered microbes as whole-cell biocatalysts.

Identifiers

PMID29056821
PMCPMC5647830

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.