Evidence map›Paper›PMID 29056541›Full record

ArticleEBioMedicine2017

Application of Convolutional Neural Networks in the Diagnosis of Helicobacter pylori Infection Based on Endoscopic Images.

Satoki Shichijo, Shuhei Nomura, Kazuharu Aoyama, Yoshitaka Nishikawa, Motoi Miura, Takahide Shinagawa, Hirotoshi Takiyama, Tetsuya Tanimoto, Soichiro Ishihara, Keigo Matsuo and 1 more

Abstract read
In one paragraph

Article in EBioMedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

118 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Artificial intelligence in gastric cancer: a systematic review.Journal of cancer research and clinical oncology · 2020
    Pooled it
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  15. Limited discriminative performance of endoscopic deep learning forFrontiers in gastroenterology (Lausanne, Switzerland) · 2026
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Role of artificial intelligence in gastric diseases.World journal of gastroenterology · 2025
    Review

58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Satoki ShichijoTada Tomohiro Institute of Gastroenterology and Proctology, Japan; Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Japan. Electronic address: shichijiyou-tky@umin.ac.jp.
Shuhei NomuraDepartment of Global Health Policy, Graduate School of Medicine, The University of Tokyo, Japan; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK.
Kazuharu AoyamaIdee, Inc., Japan.
Yoshitaka NishikawaDepartment of Health Informatics, Kyoto University School of Public Health, Japan.
Motoi MiuraTada Tomohiro Institute of Gastroenterology and Proctology, Japan; Teikyo University of Graduate School of Public Health, Japan.
Takahide ShinagawaTada Tomohiro Institute of Gastroenterology and Proctology, Japan; Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Hirotoshi TakiyamaTada Tomohiro Institute of Gastroenterology and Proctology, Japan; Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Tetsuya TanimotoMedical Governance Research Institute, Japan; Jyoban Hospital of Tokiwa Foundation, Japan.
Soichiro IshiharaTada Tomohiro Institute of Gastroenterology and Proctology, Japan; Surgery Department, Sanno Hospital, International University of Health and Welfare, Japan.
Keigo MatsuoDepartment of Gastroenterology, Tokatsu-Tsujinaka Hospital, Japan.
Tomohiro TadaTada Tomohiro Institute of Gastroenterology and Proctology, Japan; Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThe role of artificial intelligence in the diagnosis of Helicobacter pylori gastritis based on endoscopic images has not been evaluated. We constructed a convolutional neural network (CNN), and evaluated its ability to diagnose H. pylori infection.

methodsA 22-layer, deep CNN was pre-trained and fine-tuned on a dataset of 32,208 images either positive or negative for H. pylori (first CNN). Another CNN was trained using images classified according to 8 anatomical locations (secondary CNN). A separate test data set (11,481 images from 397 patients) was evaluated by the CNN, and 23 endoscopists, independently.

resultsThe sensitivity, specificity, accuracy, and diagnostic time were 81.9%, 83.4%, 83.1%, and 198s, respectively, for the first CNN, and 88.9%, 87.4%, 87.7%, and 194s, respectively, for the secondary CNN. These values for the 23 endoscopists were 79.0%, 83.2%, 82.4%, and 230±65min (85.2%, 89.3%, 88.6%, and 253±92min by 6 board-certified endoscopists), respectively. The secondary CNN had a significantly higher accuracy than endoscopists (by 5.3%; 95% CI, 0.3-10.2).

conclusionH. pylori gastritis could be diagnosed based on endoscopic images using CNN with higher accuracy and in a considerably shorter time compared to manual diagnosis by endoscopists.

Indexed as

Artificial IntelligenceEndoscopy, GastrointestinalFemaleGastritisHelicobacter InfectionsHelicobacter pyloriHumansImage Processing, Computer-AssistedMaleMiddle AgedNeural Networks, ComputerArtificial intelligenceConvolutional neural networksEndoscopyHelicobacter pylori

Identifiers

PMID29056541
PMCPMC5704071

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.