Evidence map›Paper›PMID 29055782›Full record

ArticleContraception2018

Interest in multipurpose prevention technologies to prevent HIV/STIs and unintended pregnancy among young women in the United States.

Jenna S Hynes, Jessica M Sales, Anandi N Sheth, Eva Lathrop, Lisa B Haddad

Abstract read
In one paragraph

Article in Contraception, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  5. SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jenna S HynesEmory University School of Medicine, Department of Gynecology and Obstetrics, 49 Jesse Hill Jr. Drive, NE, Faculty Office Building, Atlanta, GA 30322, USA. Electronic address: jenna.s.hynes@gmail.com.
Jessica M SalesRollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322, USA. Electronic address: jmcderm@emory.edu.
Anandi N ShethEmory University School of Medicine, Department of Medicine, Division of Infectious Diseases, 201 Dowman Drive, Atlanta, GA 30322, USA. Electronic address: ansheth@emory.edu.
Eva LathropEmory University School of Medicine, Department of Gynecology and Obstetrics, 49 Jesse Hill Jr. Drive, NE, Faculty Office Building, Atlanta, GA 30322, USA. Electronic address: elathro@emory.edu.
Lisa B HaddadEmory University School of Medicine, Department of Gynecology and Obstetrics, 49 Jesse Hill Jr. Drive, NE, Faculty Office Building, Atlanta, GA 30322, USA. Electronic address: lisa.haddad@emory.edu.

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Characterization and modulation of mucosal immunity for HIV prevention in womenK23AI114407 · NIAID · EMORY UNIVERSITY · PI SHETH, ANANDI NAYAN · 2014 to 2018
$898k
Impact of progestin contraception on risk of HIV acquisition and transmissionK23HD078153 · NICHD · EMORY UNIVERSITY · PI HADDAD, LISA BLAKE · 2014 to 2018
$704k
NCATS NIH HHS UL1 TR000454NIAID NIH HHS K23 AI114407NIAID NIH HHS P30 AI050409NICHD NIH HHS K23 HD078153
6 · The paper itself

Abstract

objectiveHigh rates of sexually transmitted infections (STIs) and unintended pregnancy suggest a role for multipurpose prevention technologies (MPTs) designed to combine contraception and infection prophylaxis into one unified method. This study aims to determine factors associated with interest in MPTs among US women. STUDY

designWe administered a national cross-sectional survey via MTurk. Eligibility criteria included female gender, age 18-29 years, residence in the USA, and sexual activity with a male partner in the past three months. In total, 835 surveys were suitable for analysis. Bivariable and multivariable logistic regressions were performed to determine factors associated with interest in MPTs.

resultsEighty-three percent of women were interested in MPTs. Factors associated with interest included oral sex in the past three months (aOR 1.87, 95% CI 1.07, 3.53), recent use of oral contraceptive pills (OCPs; aOR 1.78, 95% CI 1.08, 2.93), HIV test within one year (aOR 2.10, 95% CI 1.29, 3.40), and increased STI worry score (aOR 1.98, 95% CI 1.36, 2.86). No use of contraception in the past three months was associated with decreased interest in MPTs (aOR 0.31, 95% CI 0.17, 0.58). HIV risk factors including race were not associated with MPT interest.

conclusionOur data show that young, sexually active, US women are interested in MPTs. Women who used contraception, specifically OCPs, or evidenced concern for infection were most likely to be interested in such a product. Women reporting unsafe sexual habits were less likely to be interested, highlighting the importance of HIV/STI prevention education. IMPLICATIONS: Women in the USA are interested in multipurpose prevention technologies, particularly those women who currently use contraception or are concerned about their risk of infection. Our results emphasize the importance of moving forward with MPT development as well as continued HIV/STI prevention education.

Indexed as

Attitude to HealthAdolescentAdultContraceptionCross-Sectional StudiesFemaleHIVHIV InfectionsHumansLogistic ModelsMultivariate AnalysisPregnancyPregnancy, UnplannedPrimary PreventionSexual BehaviorSexually Transmitted DiseasesContraceptionHIV prophylaxisMultipurpose prevention technologiesSTIs

Identifiers

PMID29055782
PMCPMC5828781

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.