Evidence map›Paper›PMID 29055156›Full record

ArticleDiabetic medicine : a journal of the British Diabetic Association2018

Type 2 diabetes remission 2 years post Roux-en-Y gastric bypass and sleeve gastrectomy: the role of the weight loss and comparison of DiaRem and DiaBetter scores.

A Pucci, U Tymoszuk, W H Cheung, J M Makaronidis, S Scholes, G Tharakan, M Elkalaawy, M Guimaraes, M Nora, M Hashemi and 5 more

Open access · hybridAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetic medicine : a journal of the British Diabetic Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 3 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 3 syntheses or guidelines pooled it, 99 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Observational
  8. Observational
  9. Article
  10. Type 2 Diabetes Mellitus Remission, Dream or Reality? A Narrative Review of Current Evidence and Integrated Care Strategies.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Towards precision medicine in bariatric surgery prescription.Reviews in endocrine & metabolic disorders · 2023
    Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

A PucciCentre for Obesity Research, Rayne Institute, University College London, London, UK.
U TymoszukDepartment of Epidemiology & Public Health, London, UK.
W H CheungCentre for Obesity Research, Rayne Institute, University College London, London, UK.
J M MakaronidisCentre for Obesity Research, Rayne Institute, University College London, London, UK.
S ScholesDepartment of Epidemiology & Public Health, London, UK.
G TharakanDepartment of Endocrinology, Imperial College Healthcare NHS Trust, London, UK.
M ElkalaawyUniversity College London Hospital Bariatric, Centre for Weight Management and Metabolic Surgery, London, UK.
M GuimaraesDepartment of General Surgery, Centro Hospitalar de Entre o Douro e Vouga, Santa Maria da Feira, Portugal.
M NoraDepartment of General Surgery, Centro Hospitalar de Entre o Douro e Vouga, Santa Maria da Feira, Portugal.
M HashemiUniversity College London Hospital Bariatric, Centre for Weight Management and Metabolic Surgery, London, UK.
A JenkinsonUniversity College London Hospital Bariatric, Centre for Weight Management and Metabolic Surgery, London, UK.
M AdamoUniversity College London Hospital Bariatric, Centre for Weight Management and Metabolic Surgery, London, UK.
M P MonteiroClinical and Experimental Endocrinology, Department of Anatomy, Multidisciplinary Unit for Biomedical Research (UMIB), Instituto de Ciências Biomédicas Abel Salazar, University of Porto, Porto, Portugal.
N FinerCentre for Obesity Research, Rayne Institute, University College London, London, UK.
R L BatterhamCentre for Obesity Research, Rayne Institute, University College London, London, UK.ORCID 0000-0002-5477-8585
University College Hospital · GBPublic Health England · GBUnidade Local de Saúde de Entre Douro e Vouga · PTImperial College Healthcare NHS Trust · GBUniversidade do Porto · PT

Funding

Department of Health RP-2015-06-005
6 · The paper itself

Abstract

aimsThe comparative efficacy of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy on Type 2 diabetes remission and the role of weight loss are unclear. The DiaRem diabetes remission prediction score uses HbA

methodsA retrospective single-centre cohort study of obese people with diabetes who underwent RYGB (107) or sleeve gastrectomy (103) and a validation cohort study (173) were undertaken. Diabetes remission, % weight loss, DiaRem, DiaBetter scores and areas under receiving operator characteristic (ROC) curves were calculated. The relationship between % weight loss and diabetes remission was investigated using logistic regression.

resultsThe proportion of people achieving diabetes remission was highest for those with the lowest DiaBetter and DiaRem scores. Areas under the ROC curves were comparable [DiaBetter: 0.867 (95%CI: 0.817-0.916); DiaRem: 0.865 (95%CI: 0.814-0.915), P=0.856]. Two-year % weight loss was higher post RYGB [26.6 (95%CI: 24.8-28.4)] vs post-sleeve gastrectomy [20.6 (95%CI: 18.3-22.8), P<0.001]. RYGB had 151% higher odds of diabetes remission [OR 2.51 (95%CI: 1.12-5.60), P=0.025]. This association became non-significant when adjusted for % weight loss.

conclusionDiaBetter and DiaRem scores predict diabetes remission following both procedures. Two-year % weight loss plays a key role in determining diabetes remission.

Indexed as

Bariatric SurgeryDiabetes Mellitus, Type 2FemaleGastrectomyGastric BypassGlycated HemoglobinHumansMaleMiddle AgedProbabilityRemission InductionTreatment OutcomeWeight LossGlycated Hemoglobin

Identifiers

PMID29055156
PMCPMC5836992
OpenAlexW2767152511

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.