ArticlePlant biotechnology journal2018
PpNAC1, a main regulator of phenylalanine biosynthesis and utilization in maritime pine.
Article in Plant biotechnology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 75 citations in OpenAlex.
- Identification of thePlants (Basel, Switzerland) · 2026Article
- Heterologous expression of Pinus massoniana VNS2 enhances secondary cell wall deposition in poplar.Plant cell reports · 2026Article
- Arginine, a key amino acid for nitrogen nutrition and metabolism of forest trees.Journal of experimental botany · 2025Review
- Evolution of NAC transcription factors from early land plants to domesticated crops.Plant & cell physiology · 2025Article
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- Unveiling Key Genes and Unique Transcription Factors Involved in Secondary Cell Wall Formation inInternational journal of molecular sciences · 2024Article
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- The transcription factor VviNAC60 regulates senescence- and ripening-related processes in grapevine.Plant physiology · 2023Article
- Gene enrichment and co-expression analysis shed light on transcriptional responses to Ralstonia solanacearum in tomato.BMC genomics · 2023Article
- Meliaceae genomes provide insights into wood development and limonoids biosynthesis.Plant biotechnology journal · 2023Article
- FvNST1b NAC Protein Induces Secondary Cell Wall Formation in Strawberry.International journal of molecular sciences · 2022Article
- Protoplast isolation and transcriptome analysis of developing xylem in Pinus massoniana (Pinaceae).Molecular biology reports · 2022Article
- Characterization and Interaction Analysis of the Secondary Cell Wall Synthesis-Related Transcription FactorInternational journal of molecular sciences · 2022Article
- Full-Length Transcriptome Sequencing and Comparative Transcriptomic Analyses Provide Comprehensive Insight Into Molecular Mechanisms of Cellulose and Lignin Biosynthesis inFrontiers in plant science · 2022Article
- Comprehensive genomic characterization of NAC transcription factor family and their response to salt and drought stress in peanut.BMC plant biology · 2020Article
- Transcriptional analysis of arogenate dehydratase genes identifies a link between phenylalanine biosynthesis and lignin biosynthesis.Journal of experimental botany · 2020Article
- Induction of PrMADS10 on the lower side of bent pine tree stems: potential role in modifying plant cell wall properties and wood anatomy.Scientific reports · 2019Article
- Analysis of OrthologousInternational journal of molecular sciences · 2019Article
- Functional Analysis of theFrontiers in plant science · 2019Article
- Recent Advances in the Transcriptional Regulation of Secondary Cell Wall Biosynthesis in the Woody Plants.Frontiers in plant science · 2018Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The transcriptional regulation of phenylalanine metabolism is particularly important in conifers, long-lived species that use large amounts of carbon in wood. Here, we show that the Pinus pinaster transcription factor, PpNAC1, is a main regulator of phenylalanine biosynthesis and utilization. A phylogenetic analysis classified PpNAC1 in the NST proteins group and was selected for functional characterization. PpNAC1 is predominantly expressed in the secondary xylem and compression wood of adult trees. Silencing of PpNAC1 in P. pinaster results in the alteration of stem vascular radial patterning and the down-regulation of several genes associated with cell wall biogenesis and secondary metabolism. Furthermore, transactivation and EMSA analyses showed that PpNAC1 is able to activate its own expression and PpMyb4 promoter, while PpMyb4 is able to activate PpMyb8, a transcriptional regulator of phenylalanine and lignin biosynthesis in maritime pine. Together, these results suggest that PpNAC1 is a functional ortholog of the ArabidopsisSND1 and NST1 genes and support the idea that key regulators governing secondary cell wall formation could be conserved between gymnosperms and angiosperms. Understanding the molecular switches controlling wood formation is of paramount importance for fundamental tree biology and paves the way for applications in conifer biotechnology.
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