Evidence map›Paper›PMID 29054857›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2018

Diazepam Concurrently Increases the Frequency and Decreases the Amplitude of Transient Dopamine Release Events in the Nucleus Accumbens.

Scott A Schelp, Zachary D Brodnik, Dylan R Rakowski, Katherine J Pultorak, Asha T Sambells, Rodrigo A España, Erik B Oleson

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
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  7. Drug-Drug Interactions in Vestibular Diseases, Clinical Problems, and Medico-Legal Implications.International journal of environmental research and public health · 2021
    Review
  8. Dopamine, behavior, and addiction.Journal of biomedical science · 2021
    Review
  9. Review
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Scott A SchelpUniversity of Colorado Denver, Department of Psychology, Denver, Colorado (S.A.S., D.R.R., K.J.P., A.T.S., E.B.O.) and Drexel University College of Medicine, Department of Neurobiology and Anatomy, Philadelphia, Pennsylvania (Z.D.R., R.A.E.).
Zachary D BrodnikUniversity of Colorado Denver, Department of Psychology, Denver, Colorado (S.A.S., D.R.R., K.J.P., A.T.S., E.B.O.) and Drexel University College of Medicine, Department of Neurobiology and Anatomy, Philadelphia, Pennsylvania (Z.D.R., R.A.E.).
Dylan R RakowskiUniversity of Colorado Denver, Department of Psychology, Denver, Colorado (S.A.S., D.R.R., K.J.P., A.T.S., E.B.O.) and Drexel University College of Medicine, Department of Neurobiology and Anatomy, Philadelphia, Pennsylvania (Z.D.R., R.A.E.).
Katherine J PultorakUniversity of Colorado Denver, Department of Psychology, Denver, Colorado (S.A.S., D.R.R., K.J.P., A.T.S., E.B.O.) and Drexel University College of Medicine, Department of Neurobiology and Anatomy, Philadelphia, Pennsylvania (Z.D.R., R.A.E.).
Asha T SambellsUniversity of Colorado Denver, Department of Psychology, Denver, Colorado (S.A.S., D.R.R., K.J.P., A.T.S., E.B.O.) and Drexel University College of Medicine, Department of Neurobiology and Anatomy, Philadelphia, Pennsylvania (Z.D.R., R.A.E.).
Rodrigo A EspañaUniversity of Colorado Denver, Department of Psychology, Denver, Colorado (S.A.S., D.R.R., K.J.P., A.T.S., E.B.O.) and Drexel University College of Medicine, Department of Neurobiology and Anatomy, Philadelphia, Pennsylvania (Z.D.R., R.A.E.).
Erik B OlesonUniversity of Colorado Denver, Department of Psychology, Denver, Colorado (S.A.S., D.R.R., K.J.P., A.T.S., E.B.O.) and Drexel University College of Medicine, Department of Neurobiology and Anatomy, Philadelphia, Pennsylvania (Z.D.R., R.A.E.) erik.oleson@ucdenver.edu.
Drexel University · USUniversity of Colorado Denver · US

Funding

Involvement of hypocretin-orexin in the regulation of dopamine signaling and reinforcement processes in femalesR01DA031900 · NIDA · DREXEL UNIVERSITY · PI ESPAÑA, RODRIGO A. · 2013 to 2022
$3.6M
Potential Role of Phasic Dopamine and Endocannabinoids in Conditioned WithdrawalR03DA038734 · NIDA · UNIVERSITY OF COLORADO DENVER · PI OLESON, ERIK BENJAMIN · 2015 to 2015
$117k
NIDA NIH HHS R01 DA031900NIDA NIH HHS R03 DA038734
6 · The paper itself

Abstract

Benzodiazepines are commonly prescribed anxiolytics that pose abuse liability in susceptible individuals. Although it is well established that all drugs of abuse increase brain dopamine levels, and benzodiazepines are allosteric modulators of the GABA

Indexed as

AnimalsDiazepamDopamineFlumazenilMaleNucleus AccumbensRatsTime FactorsDiazepamDopamineFlumazenil

Identifiers

PMID29054857
PMCPMC5741045
OpenAlexW2765549027

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.