Evidence map›Paper›PMID 29054482›Full record

ArticleDiabetes research and clinical practice2017

The effectiveness of an obstructive sleep apnea screening and treatment program in patients with type 2 diabetes.

Lucas M Donovan, Michael Rueschman, Jia Weng, Nisha Basu, Katherine A Dudley, Jessie P Bakker, Rui Wang, Suzanne M Bertisch, Sanjay R Patel

Open access · greenAbstract read
In one paragraph

Article in Diabetes research and clinical practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Diagnosis of Obstructive Sleep Apnea in Patients with Associated Comorbidity.Advances in experimental medicine and biology · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The Epidemiology of Sleep and Diabetes.Current diabetes reports · 2018
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Lucas M DonovanUniversity of Washington, 1959 NE Pacific St, Seattle, WA 98195, United States. Electronic address: ldonovan@uw.edu.
Michael RueschmanBrigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States. Electronic address: mrueschman@bwh.harvard.edu.
Jia WengBrigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States. Electronic address: jweng2@partners.org.
Nisha BasuBeth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02115, United States. Electronic address: nbasu@bidmc.harvard.edu.
Katherine A DudleyBeth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02115, United States. Electronic address: kdudley@bidmc.harvard.edu.
Jessie P BakkerBrigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States. Electronic address: jpbakker@bwh.harvard.edu.
Rui WangBrigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States. Electronic address: rwang8@partners.org.
Suzanne M BertischBeth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02115, United States. Electronic address: sbertisc@bidmc.harvard.edu.
Sanjay R PatelUniversity of Pittsburgh, UPMC Montefiore Hospital, NW628, 3459 Fifth Avenue, Pittsburgh, PA 15213, United States. Electronic address: patelsr2@upmc.edu.
Harvard University · USBeth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USUniversity of Washington · USUPMC Montefiore · US

Funding

RESPIRATORY RESEARCH TRAINING PROGRAMT32HL007287 · NHLBI · UNIVERSITY OF WASHINGTON · PI Kristina Anne Crothers, David J. Horne · 1985 to 2026
$16.7M
Mentored Patient Oriented Research in Sleep and Metabolic DiseaseK24HL127307 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PATEL, SANJAY R · 2015 to 2019
$582k
NHLBI NIH HHS K24 HL127307NHLBI NIH HHS T32 HL007287
6 · The paper itself

Abstract

aimsAs recommended by current guidelines, we tested the acceptability and impact of screening patients with type 2 diabetes for obstructive sleep apnea (OSA).

methodsIn a large urban primary care practice, we instituted a telephone-based OSA screening program using a validated tool (STOP-BANG) in patients with type 2 diabetes. Patients identified as high risk were referred for diagnostic sleep testing, and those diagnosed with OSA were offered positive airway pressure (PAP) therapy. We evaluated the impact of PAP on sleep-related symptoms, glycemic control, and hospitalization rates.

resultsWe identified 738 of 818 (90.1%) patients with type 2 diabetes as high risk for OSA. Only 29.2% (n = 213) of high risk patients were willing to undergo diagnostic sleep testing. The prevalence of OSA was 90.6% in this group, but only 66.0% of those with OSA initiated PAP. Patients with higher burden of sleep symptoms were more likely to pursue testing and initiate therapy. PAP use was associated with reduced sleep-related symptoms (mean Epworth sleepiness scale score declined from 8.8 to 7.3, p < .001), but did not impact hemoglobin A1c levels at one year (7.7-7.9%, p = .12). Changes in glycemic control and hospitalization rates did not differ from comparator groups.

conclusionsDespite a high prevalence of OSA, willingness to pursue diagnostic testing and treatment was low in an unselected type 2 diabetes population. Furthermore, glycemic control did not improve. Future screening programs should focus on patients with substantial sleep related symptoms as this group is most likely to derive benefit from treatment.

Indexed as

Diabetes Mellitus, Type 2FemaleHumansMaleMass ScreeningMiddle AgedSleep Apnea, ObstructiveSurveys and QuestionnairesDiabetesScreeningSleep apnea

Identifiers

PMID29054482
PMCPMC5724386
OpenAlexW2765848181

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.